Delmopinol

• CAS: 79874-76-3
• Catalog Number: ACM79874763
• Category: Main Products
• Molecular Weight: 0
• Molecular Formula: C₁₆H₃₃NO₂
• Synonyms: Delmopinol;(+-)-3-(4-Propylheptyl)-4-morpholineethanol;Decapinol;(Rs)-2-(3-(4-propylheptyl)morpholino)ethanol;4-Morpholineethanol, 3-(4-propylheptyl)-, ( -)-;Decapinolum;Delmopinolum;Delmopinolum [inn-latin]
• IUPAC Name: 2-[3-(4-propylheptyl)morpholin-4-yl]ethanol
• Canonical SMILES: CCCC(CCC)CCCC1COCCN1CCO
• InChI Key: QSFOWAYMMZCQNF-UHFFFAOYSA-N
• Boiling Point: 374.6ºC at 760 mmHg
• Flash Point: 180.3ºC
• Density: 0.924g/cm³
• Exact Mass: 271.25100

Case Study

Delmopinol Reduces Acid Tolerance and Production in Plaque Biofilm Bacteria When Combined with Fluoride

Neilands J, et al. Archives of Oral Biology, 2014, 59(3), 18-323.

Delmopinol has demonstrated significant potential in dental care applications, particularly when combined with fluoride. This study explored the effects of delmopinol and fluoride, individually and synergistically, on acid adaptation and acid production in plaque biofilm bacteria under in vitro conditions.
Biofilm bacteria were exposed to delmopinol (0.16 mM), fluoride (1 mF NaF), or their combination under static conditions at pH 5.5 to assess acid adaptation. The following day, the bacteria were challenged with an acidic environment (pH 2.5) to evaluate acid tolerance, using confocal scanning laser microscopy and LIVE/DEAD BacLight Viability staining to quantify viable cells. Acid production was measured via pH drop after glucose pulsing with various concentrations of delmopinol and fluoride.
The findings revealed that fluoride alone significantly reduced acid tolerance and acid production. Notably, a combination of delmopinol and fluoride had a more pronounced inhibitory effect on acid adaptation and acid production, even at concentrations where the individual compounds were ineffective. Delmopinol alone did not impact acid adaptation or acid production.

Custom Q&A

What is the molecular formula of Delmopinol?

The molecular formula of Delmopinol is C16H33NO2.

What are some synonyms for Delmopinol?

Some synonyms for Delmopinol are Decapinol, Delmopinolum, delmopinol HCl, and 2-[3-(4-propylheptyl)morpholin-4-yl]ethanol.

What is the CAS number of Delmopinol?

The CAS number of Delmopinol is 79874-76-3.

What is the IUPAC name of Delmopinol?

The IUPAC name of Delmopinol is 2-[3-(4-propylheptyl)morpholin-4-yl]ethanol.

What is the InChIKey of Delmopinol?

The InChIKey of Delmopinol is QSFOWAYMMZCQNF-UHFFFAOYSA-N.

What is the molecular weight of Delmopinol?

The molecular weight of Delmopinol is 271.44g/mol.

How many hydrogen bond donor count does Delmopinol have?

Delmopinol has 1 hydrogen bond donor count.

How many hydrogen bond acceptor count does Delmopinol have?

Delmopinol has 3 hydrogen bond acceptor count.

How many rotatable bond count does Delmopinol have?

Delmopinol has 10 rotatable bond count.

What is the topological polar surface area of Delmopinol?

The topological polar surface area of Delmopinol is 32.7Ų.