Gas Chromatography (GC)

Gas Chromatography (GC)

GC is a powerful analytical technique used for separating and analyzing volatile compounds with high efficiency and sensitivity. It is a crucial tool in many industries, providing critical data for quality control, research, and deformulation.

Gas chromatography (GC) is a common technique used in analytical chemistry to separate and analyze compounds that can be vaporized without decomposition. In GC, a sample is vaporized and injected into a column that is packed with a stationary phase (liquid or solid) and a carrier gas (typically helium). As the sample travels through the column, it interacts with the stationary phase and separates into its components based on their different affinities for the stationary phase. The separated components are then detected and quantified using a detector such as a flame ionization detector (FID) or mass spectrometer. GC is widely used in various industries such as pharmaceuticals, environmental analysis, food industry and forensic science for the analysis of complex mixtures.

Fig. 1. Image of gas chromatograph.

What is GC Used For?

Gas chromatography is intensively used in research and industrial laboratories for separating and analysing compounds that can be vaporized without decomposition. Therefore, GC is highly suitable for the separation and quantitative analysis of virtually any semi-volatile and volatile compound, and gases. Based on this,

  • It is used to test the purity of a particular substance or to separate different components of a mixture.
  • It is used to test for trace impurities in a compound or in a mixture.
  • It is used to identify additives present in a sample.
  • It is commonly used for separation and identification of solvents.

Application of GC in Deformulation

GC is a powerful analytical technique that is often used in deformulation to separate and analyze the individual components of a sample. This allows for the identification of the active ingredients present in a product, detecting and quantifying impurities or contaminants in a formulation, analyzing complex mixtures, etc. This is providing valuable information about the composition and quality of a product. Importantly, GC helps to identify volatile organic components present in a formulation, useful for understanding the 'volatile profile' of a product which can aid in product improvement and cost reduction in manufacturing.

How We Can Help You?

Understanding the complexities of GC and utilizing it for deformulation can be a challenging process. Our team of specialized scientists and technicians have extensive experience in this field. We equipped with state-of-the-art GC equipment, and various gas chromatography detectors, including:

  • Flame ionization detector (FID)
  • Thermal conductivity detector (TCD)
  • Electron capture detector (ECD)
  • Flame photometric detector (FPD)
  • Pulsed discharge helium ionization detector (HID)
  • Mass spectrometer (MS)
  • Nitrogen-phosphorus detector (NPD)
  • Atomic emission detector (AED)
  • Infrared detector (IRD).
  • ...

Based on this, we provide GC analysis services catering not only to routine testing but also to more complex analysis such as deformulation analysis. Our progressive approach ensures that you get accurate results which are pertinent to your research and development process. Our services also extend to interpretation of the results and consultation on the next steps, ensuring that you derive maximum value from the analysis.

If you're seeking to identify unknown substances or contaminants, develop new products or improve existing ones, or to meet regulatory requirements, our GC and deformulation services can offer the crucial insight your project needs.

Please kindly note that our products and services are for research use only.

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