7-Hydroxy-5-methyl-2-methylthio-s-triazolo[1,5-a]pyrimidine

CAS

40775-78-8

Catalog Number

ACM40775788

Category

Other Products

Molecular Weight

196.23

Molecular Formula

C₇H₈N₄OS

MSDS COA Spec Sheet

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Specification

Synonyms

2,4]triazolo[1,5-a]pyrimidin-7-ol,5-methyl-2-(methylthio)-[;2,4]Triazolo[1,5-a]pyrimidin-7-ol,5-methyl-2-(methylthio)-[1;hydroxymethylmethylthiotriazolopyrimidine;AURORA KA-421;4-HYDROXY-6-METHYL-2-METHYLMERCAPTO-1,3,3A,7-TETRAAZAINDENE;7-HYDROXY-5-METHY

IUPAC Name

5-methyl-2-methylsulfanyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

InChI Key

DITIBSDLGMCMTP-UHFFFAOYSA-N

Boiling Point

302.5ºC at 760 mmHg

Melting Point

300ºC

Flash Point

136.7ºC

Density

1.59g/cm³

Exact Mass

196.04200

H-Bond Acceptor

H-Bond Donor

Safety Description

S24/25

Downstream Synthesis Route 1

40775-78-8

1163260-88-5

Reference: [1]Current Patent Assignee: MMV MEDICINES FOR MALARIA VENTURE PPP - WO2011/41304, 2011, A2
[2]Coteron, Jose M.; Marco, María; Esquivias, Jorge; Deng, Xiaoyi; White, Karen L.; White, John; Koltun, Maria; El Mazouni, Farah; Kokkonda, Sreekanth; Katneni, Kasiram; Bhamidipati, Ravi; Shackleford, David M.; Angulo-Barturen, Iñigo; Ferrer, Santiago B.; Jiménez-Díaz, María Belén; Gamo, Francisco-Javier; Goldsmith, Elizabeth J.; Charman, William N.; Bathurst, Ian; Floyd, David; Matthews, David; Burrows, Jeremy N.; Rathod, Pradipsinh K.; Charman, Susan A.; Phillips, Margaret A.
[Journal of Medicinal Chemistry, 2011, vol. 54, # 15, p. 5540 - 5561]

Downstream Synthesis Route 2

40775-78-8

101251-18-7

Reference: [1]Location in patent: experimental part
Coteron, Jose M.; Marco, María; Esquivias, Jorge; Deng, Xiaoyi; White, Karen L.; White, John; Koltun, Maria; El Mazouni, Farah; Kokkonda, Sreekanth; Katneni, Kasiram; Bhamidipati, Ravi; Shackleford, David M.; Angulo-Barturen, Iñigo; Ferrer, Santiago B.; Jiménez-Díaz, María Belén; Gamo, Francisco-Javier; Goldsmith, Elizabeth J.; Charman, William N.; Bathurst, Ian; Floyd, David; Matthews, David; Burrows, Jeremy N.; Rathod, Pradipsinh K.; Charman, Susan A.; Phillips, Margaret A.
[Journal of Medicinal Chemistry, 2011, vol. 54, # 15, p. 5540 - 5561]
[2]Current Patent Assignee: MMV MEDICINES FOR MALARIA VENTURE PPP - WO2011/41304, 2011, A2
Location in patent: Page/Page column 36-37