Aluminum chlorohydrate

• CAS: 1327-41-9
• Catalog Number: ACM1327419
• Category: Main Products
• Molecular Weight: 79.44
• Molecular Formula: AlClH₂O
• Synonyms: Aluminum hydroxychloride
• Appearance: Yellow solid
• Assay: 0.99
• Packaging: 1 kg
• Stability: Stable. Incompatible with many metals.

Case Study

Aluminum Chlorohydrate Coagulant for the Determination and Removal of Pharmaceuticals and Total Organic Carbon

Kuc J, et al. Molecules, 2022, 27(17), 5740.

Aluminum chlorohydrate (ACH) was used as a coagulant to remove total organic carbon (TOC) and erythromycin (ERY), fluoxetine (FLX), amoxicillin (AMO), colistin (COL), ethinyl estradiol (EE) and diclofenac (DIC) from surface water by coagulation. The study found that under the optimal coagulation process conditions, the concentrations of TOC, ERY, FLX, AMO, COL, EE and DIC in surface water samples treated with ACH were reduced by 88.7%, 36.4%, 24.7%, 29.0%, 25.5%, 35.4% and 30.4%, respectively.
Experimental methods
The experiments were conducted using 600 mL beakers equipped with magnetic stirrers that allowed for adjustable mixing speeds. For each trial, 500 mL of spiked river water was poured into the beaker, followed by the addition of a specified dosage of ACH and adjustments made to reach the desired pH level. The pH corrections for the treated water were achieved with a 15% solution of NaOH or H2SO4. The water was then stirred for a predetermined duration. After this period, stirring was halted, and the samples were allowed to settle for 30 minutes to enable the precipitation of sludge. Turbidity and total suspended solids (TSS) were assessed using unfiltered samples, while other parameters were measured on water that had been filtered through a 0.45 μm syringe filter. Prior to RP-HPLC-ESI-MS/MS analysis, the samples were also filtered through a 0.22 μm syringe filter. The concentration of total organic carbon (TOC) was analyzed to evaluate the effectiveness of TOC removal in each experiment.

Effect of Antiperspirant Aluminum Chloride on Antibiotic Resistance of Staphylococcus Epidermidis

Aras, Ayse, et al. Microorganisms, 2023, 11(4), 948.

Aluminum chlorohydrate (ACH) is an inorganic salt composed of complex basic aluminum chloride and is widely used as an antiperspirant. This work studied the effect of aluminum chlorohydrate on antibiotic resistance of Staphylococcus epidermidis, a normal human axillary flora.
Experimental methods and results
· A 40 μL volume of the bacterial suspension (adjusted to 10^8-10^9 cfu mL-1) was introduced into 3.96 mL of LB medium containing aluminum chlorohydrate at a concentration of 300 mg/L. Following incubation at 37 °C for 18-24 hours, 40 μL of the bacterial culture was transferred to another 3.96 mL of fresh LB with the same aluminum chlorohydrate concentration for further incubation. This process was repeated continuously for a span of 30 days. On the 10th and 30th days, 100 μL of the bacterial samples exposed to the aluminum chlorohydrate were plated onto MHA plates supplemented with 0.5 μg mL-1 oxacillin and 4 μg mL-1 ciprofloxacin.
· Alongside the observed ciprofloxacin resistance, there was a noticeable increase in the expression of the norA, norB/C, gyrA, gyrB, parC, and parE genes. Furthermore, all test bacteria in the group that was solely subcultured in the medium exhibited oxacillin resistance, indicating that phenotypic resistance may not be linked to chemical exposure based on these findings. The heightened expression of the mecA gene in certain test bacteria, which developed resistance to oxacillin after exposure, compared to control groups, suggests a potential association between the observed resistance and aluminum chlorohydrate exposure.

Custom Q&A

What is the molecular formula of aluminum chlorohydrate?

The molecular formula of aluminum chlorohydrate is Al2ClH9O7.

What are some synonyms for aluminum chlorohydrate?

Some synonyms for aluminum chlorohydrate include Alchlordrate, Phosphonorm, Oristar alch, Sumalchlor 50, HYPERDROL, and Takibine 1500.

What is the InChI of aluminum chlorohydrate?

The InChI of aluminum chlorohydrate is InChI=1S/2Al.ClH.7H2O/h;;1H;7*1H2/q2*+3;;;;;;;;/p-6.

What is the CAS number of aluminum chlorohydrate?

The CAS number of aluminum chlorohydrate is 12359-72-7.

What is the molecular weight of aluminum chlorohydrate?

The molecular weight of aluminum chlorohydrate is 210.48 g/mol.

How many hydrogen bond donor counts does aluminum chlorohydrate have?

Aluminum chlorohydrate has 7 hydrogen bond donor counts.

How many hydrogen bond acceptor counts does aluminum chlorohydrate have?

Aluminum chlorohydrate has 8 hydrogen bond acceptor counts.

What is the topological polar surface area of aluminum chlorohydrate?

The topological polar surface area of aluminum chlorohydrate is 7Ų.

How many heavy atoms are in aluminum chlorohydrate?

There are 10 heavy atoms in aluminum chlorohydrate.

Is the compound canonicalized?

Yes, the compound aluminum chlorohydrate is canonicalized.