3-hydroxypyrazine-2-carboxamide

• CAS: 55321-99-8
• Catalog Number: ACM55321998
• Category: Pyrazines
• Molecular Weight: 139.1
• Molecular Formula: C5H5N3O2
• Appearance: Brown Powder

Custom Q&A

What is the molecular formula of 3-hydroxypyrazine-2-carboxamide?

The molecular formula is C5H5N3O2.

What are some synonyms for 3-hydroxypyrazine-2-carboxamide?

Some synonyms include T-1105, 2-oxo-1H-pyrazine-3-carboxamide, and 3-Oxo-3,4-dihydropyrazine-2-carboxamide.

What is the molecular weight of 3-hydroxypyrazine-2-carboxamide?

The molecular weight is 139.11 g/mol.

When was 3-hydroxypyrazine-2-carboxamide first created in the PubChem database?

It was first created on March 26, 2005.

What is the InChIKey for 3-hydroxypyrazine-2-carboxamide?

The InChIKey is SZPBAPFUXAADQV-UHFFFAOYSA-N.

How many hydrogen bond donor counts does 3-hydroxypyrazine-2-carboxamide have?

It has 2 hydrogen bond donor counts.

What is the topological polar surface area of 3-hydroxypyrazine-2-carboxamide?

The topological polar surface area is 84.6 Å2.

How many rotatable bond counts does 3-hydroxypyrazine-2-carboxamide have?

It has 1 rotatable bond count.

What is the formal charge of 3-hydroxypyrazine-2-carboxamide?

The formal charge is 0.

Is 3-hydroxypyrazine-2-carboxamide a canonicalized compound?

Yes, it is a canonicalized compound.

Synthetic Use

Upstream Synthesis Route 1

• 131543-46-9
• 62009-47-6

• 55321-99-8

Reference: [1]Collection of Czechoslovak Chemical Communications,2011,vol. 76,p. 1327 - 1333
[2]Journal of the American Chemical Society,1956,vol. 78,p. 242

Upstream Synthesis Route 2

• 62009-47-6
• 39003-51-5

• 55321-99-8

Reference: [1]Journal of Medicinal Chemistry,1983,vol. 26,p. 283 - 286

Downstream Synthesis Route 1

• 55321-99-8

• 43029-19-2

Reference: [1] Journal of Medicinal Chemistry, 1983, vol. 26, # 2, p. 283 - 286
[2] Journal of the American Chemical Society, 1947, vol. 69, p. 1034,1035
[3] Journal of the American Chemical Society, 1956, vol. 78, p. 242
[4] Journal of the American Chemical Society, 1947, vol. 69, p. 1034,1035
[5] Journal of the American Chemical Society, 1956, vol. 78, p. 242

Downstream Synthesis Route 2

• 55321-99-8

• 55557-52-3

Reference: [1] Patent: CN104447584, 2016, B, . Location in patent: Paragraph 0138; 0139; 0140

Downstream Synthesis Route 3

• 55321-99-8

• 55557-52-3

Reference: [1] Patent: CN104447583, 2016, B, . Location in patent: Paragraph 0172; 0173; 0174; 0175

Downstream Synthesis Route 4

• 55321-99-8

• 43029-19-2

Reference: [1]Journal of Medicinal Chemistry,1983,vol. 26,p. 283 - 286
[2]Journal of the American Chemical Society,1947,vol. 69,p. 1034,1035
[3]Journal of the American Chemical Society,1947,vol. 69,p. 1034,1035
[4]Bioorganic and Medicinal Chemistry,2019,vol. 27,p. 748 - 759

* For details of the synthesis route, please refer to the original source to ensure accuracy.