Specification
Description
Z-Gly-OH, also known as N-benzyloxycarbonylglycine, is an amino acid widely used in solution phase peptide synthesis.
Canonical SMILES
OC(=O)CNC(=O)OCc1ccccc1
InChI
1S/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
InChI Key
CJUMAFVKTCBCJK-UHFFFAOYSA-N
Melting Point
118-122 ℃(lit.)
Application
Z-Gly-OH is a versatile reagent that can be used to synthesize a variety of compounds such as:
glycine-derived peptides like Z-Gly-DL-Ala-OBzl and Z-Gly-L-Ala-OBzl
glycine N-substituted amides such as glycine-N-methylamide hydrochloride and glycine-N-isopropylamide hydrochloride
Reaction Suitability
reaction type: solution phase peptide synthesis