Z-Asp(OtBu)-OH

• CAS: 5545-52-8
• Catalog Number: ACM5545528
• Category: Amino Acids
• Molecular Weight: 323.34
• Molecular Formula: (CH3)3CO2CCH2CH(NHCO2CH2C6H5)CO2H
• Synonyms: N-Cbz-L-aspartic acid 4-tert-butyl ester, Z-L-Aspartic acid 4-tert-butyl ester
• Canonical SMILES: CC(C)(C)OC(=O)C[C@H](NC(=O)OCc1ccccc1)C(O)=O
• InChI: 1S/C16H21NO6/c1-16(2,3)23-13(18)9-12(14(19)20)17-15(21)22-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,19,20)/t12-/m0/s1
• InChI Key: HLSLRFBLVZUVIE-LBPRGKRZSA-N
• Application: Peptide synthesis.
• Assay: ≥98.0% (TLC)
• Beilstein: 2569846
• Color: white
• EC Number: 226-912-0
• Form: powder or crystals
• MDL Number: MFCD00042857
• NACRES: NA.22
• PubChem ID: 329747421
• Quality Level: 100
• Reaction Suitability: reaction type: solution phase peptide synthesis
• Storage Temperature: 2-8℃

Synthetic Use

Upstream Synthesis Route 1

• 63327-57-1

• 5545-52-8

Reference: [1] Tetrahedron Letters, 2009, vol. 50, # 23, p. 2719 - 2721
[2] Synthetic Communications, 1992, vol. 22, # 6, p. 883 - 891
[3] Gazzetta Chimica Italiana, 1964, vol. 94, p. 695 - 709

Upstream Synthesis Route 2

• 23632-69-1

• 5545-52-8

Reference: [1] Tetrahedron Letters, 1993, vol. 34, # 46, p. 7409 - 7412

Downstream Synthesis Route 1

• 5545-52-8

• 1676-90-0

Reference: [1] Tetrahedron, 1972, vol. 28, p. 2649 - 2654
[2] Chemische Berichte, 1972, vol. 105, # 11, p. 3650 - 3657

Downstream Synthesis Route 2

• 186581-53-3
• 5545-52-8

• 63327-57-1

Reference: [1]Patent: US6747050,2004,B1 .Location in patent: Page/Page column 44-45

Downstream Synthesis Route 3

• 48067-24-9
• 5545-52-8

• 19246-30-1

Reference: [1]Journal of the American Chemical Society,1968,vol. 90,p. 462 - 470

Downstream Synthesis Route 4

• 48067-24-9
• 5545-52-8

• 131668-15-0

Reference: [1]Journal of the American Chemical Society,1968,vol. 90,p. 462 - 470

* For details of the synthesis route, please refer to the original source to ensure accuracy.