Wortmannin

• CAS: 19545-26-7
• Catalog Number: ACM19545267
• Category: Inhibitors
• Molecular Weight: 428.43
• Molecular Formula: C23H24O8
• Description: Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC50s of 5.8 and 48 nM, respectively.
• Synonyms: Wartmannin
• Melting Point: 237 °C
• Complexity: 921
• Defined Atom Stereocenter Count: 5
• Exact Mass: 428.1471
• Formal Charge: 0
• Heavy Atom Count: 31
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 0
• Isotope Atom Count: 0
• Monoisotopic Mass: 428.1471
• Rotatable Bond Count: 4
• Topological Polar Surface Area: 109 Ų
• XLogP3-AA: 1.2