WCK-4234 sodium

• CAS: 1804915-68-1
• Catalog Number: ACM1804915681
• Category: Inhibitors
• Molecular Weight: 269.21
• Molecular Formula: C7H8N3NaO5S
• Description: WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibited class A, C and D β-lactamases with unprecedented k2/K values against OXA carbapenemases. WCK-4234 inhibited class A, C and D β-lactamases with unprecedented k2/K values against OXA carbapenemases. WCK-4234 formed highly stable acyl-complexes via mass spectrometry. WCK-4234 is a novel β-lactamase inhibitor that demonstate potent cross-class inhibition and clinical studies targeting MDR infections are warranted.
• Synonyms: WCK-4234; WCK 4234; WCK4234
• IUPAC Name: sodium (2S,5R)-2-cyano-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
• Canonical SMILES: O=S(ON1[C@]2([H])CC[C@@H](C#N)N(C2)C1=O)([O-])=O.[Na+]
• InChI: InChI=1S/C7H9N3O5S.Na/c8-3-5-1-2-6-4-9(5)7(11)10(6)15-16(12,13)14;/h5-6H,1-2,4H2,(H,12,13,14);/q;+1/p-1/t5-,6+;/m0./s1
• InChI Key: RYJWKSOILDDAHI-RIHPBJNCSA-M
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Alternative CAS: 1804915-68-1 (sodium); 1706523-58-1 (free acid)
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 31.23; H, 3.00; N, 15.61; Na, 8.54; O, 29.72; S, 11.91
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).