Structure

Vinflunine ditartrate

CAS
194468-36-5
Catalog Number
ACM194468365
Category
Inhibitors
Molecular Weight
1117.10
Molecular Formula
C53H66F2N4O20

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Specification

Description
Vinflunine ditartrate is the first fluorinated microtubule inhibitor belonging to the Vinca alkaloids family. Vinflunine ditartrate has anti-angiogenic, vascular-disrupting and anti-metastatic activities. Vinflunine ditartrate can be used for the research of transitional cell carcinoma of the urothelial tract, non-small cell lung cancer, and carcinoma of the breast.
Synonyms
4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine Ditartrate; 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate; BMS 710485;
F 12158; Javlor
Canonical SMILES
OC([C@H](O)[C@@H](O)C(O)=O)=O.OC([C@H](O)[C@@H](O)C(O)=O)=O.CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@](C4=C5C(C=CC=C6)=C6N4)(CC(C[C@@H](C(F)(F)C)C7)([H])CN7C5)C(OC)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O
Appearance
White Solid
Storage
-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
Shipping
Can be shipped at room temperature, where not in use may vary.
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