Trichostatin a

• CAS: 58880-19-6
• Catalog Number: ACM58880196
• Category: Inhibitors
• Molecular Weight: 302.37
• Molecular Formula: C₁₇H₂₂N₂O₃
• Description: Trichostatin A (TSA) is a potent and specific inhibitor of HDAC class I/II, with an IC50 value of 1.8 nM for HDAC.
• Synonyms: (2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE;7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE;4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXAHEPTA-2,4-DIENOHYDROXAMIC ACID;4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXOHEPTA-2,4-DIENOHYDROXAMIC ACID;7-(4-(dimethylamino)phenyl)-n-hydroxy-4,6-dimethyl-7-oxo-4-heptadienamide;TSA;TRICHOSTATIN A;TRICHOSTATIN A, STREPTOMYCES SPECIES
• Melting Point: 140-143°C
• Density: 1.139
• Hazard Statements: Xn,Xi
• Safety Description: 26-36
• Supplemental Hazard Statements: H302+H312+H332-H315-H317-H319-H335
• Symbol: GHS07

Custom Q&A

What is the molecular formula of Trichostatin A?

The molecular formula of Trichostatin A is C17H22N2O3.

What is the molecular weight of Trichostatin A?

The molecular weight of Trichostatin A is 302.37 g/mol.

What is the role of Trichostatin A as per the description in the reference?

Trichostatin A is an antibiotic antifungal agent, a trichostatin, and a hydroxamic acid. It has a role as a bacterial metabolite, a geroprotector, and an EC 3.5.1.98 (histone deacetylase) inhibitor.

What is the IUPAC name of Trichostatin A?

The IUPAC name of Trichostatin A is (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide.

What is the InChIKey of Trichostatin A?

The InChIKey of Trichostatin A is RTKIYFITIVXBLE-QEQCGCAPSA-N.

How many hydrogen bond donor counts does Trichostatin A have?

Trichostatin A has 2 hydrogen bond donor counts.

How many hydrogen bond acceptor counts does Trichostatin A have?

Trichostatin A has 4 hydrogen bond acceptor counts.

How many rotatable bond counts does Trichostatin A have?

Trichostatin A has 6 rotatable bond counts.

What is the CAS number of Trichostatin A?

The CAS number of Trichostatin A is 58880-19-6.

What is the ChEMBL ID of Trichostatin A?

The ChEMBL ID of Trichostatin A is CHEMBL99.