Structure

Tobramycin

CAS
32986-56-4
Catalog Number
ACM32986564
Category
Inhibitors
Molecular Weight
467.51
Molecular Formula
C18H37N5O9

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Specification

Description
Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms.
Synonyms
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl-(1-4))-2-deoxy-
Melting Point
178°C
Active Content
95%
Hazard Statements
Xi
Physical State
Solid
Safety Description
26-37/39
What is the molecular formula of Tobramycin?

Molecular Formula: C18H37N5O9

What is the molecular weight of Tobramycin?

Molecular Weight: 467.5 g/mol

How is Tobramycin related to kanamycin B?

Tobramycin is a amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.

In what year was Tobramycin created?

Tobramycin was created in 2005.

What is the role of Tobramycin?

It has a role as an antibacterial agent, an antimicrobial agent, and a toxin.

How is Tobramycin administered for treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients?

Inhaled Tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients.

What are the characteristic toxicities associated with Tobramycin?

Characteristic toxicities include nephrotoxicity and ototoxicity.

When was Tobramycin approved by the FDA?

Tobramycin was approved by the FDA in 1975.

What are some forms in which Tobramycin is available for administration?

Tobramycin is available for administration by inhalation, injection, and external application to the eye (ophthalmic).

What is Tobramycin classified as in terms of drug type?

Tobramycin is classified as an Aminoglycoside Antibacterial.

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