CAS
2957-21-3 Purity
99.97%
2957-21-3 Purity
99.97%
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Theaflavin 3,3'-Digallate
CAS
30462-35-2
Catalog Number
ACM30462352
Category
Inhibitors
Molecular Weight
868.70
Molecular Formula
C43H32O20
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Specification
Description
Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (Kd=8.86 µM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1. Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent.
Synonyms
Tf-3
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