4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]morpholine

• CAS: 364794-80-9
• Catalog Number: ACM364794809
• Category: Other Products
• Molecular Weight: 303.2
• Molecular Formula: C₁₇H₂₆BNO₃
• Synonyms: 364794-80-9, 4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]morpholine, SBB052547, 3-(4-Methylmorpholine)benzeneboronic acid, pinacol ester, 3-(Morpholin-4-ylmethyl)benzeneboronic acid, pinacol ester, 4,4,5,5-tetramethyl-2-[3-(morpholin-4-ylmethyl)phenyl]-1,3,2-dioxaborolane, 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)morpholine, AC1MDTP1, SureCN585841, AMTB039, CTK6B2368, MolPort-000-141-064, ANW-28427, AKOS015999576, AG-C-00992, PB20970, QC-4721, RP06843, 4-[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]morpholine, AK-84225
• IUPAC Name: 4-[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]morpholine
• Canonical SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC=C2)CN3CCOCC3
• InChI Key: RCGRLLZELIIKDH-UHFFFAOYSA-N
• Boiling Point: 409.3ºC at 760mmHg
• Melting Point: 47ºC
• Flash Point: 201.4ºC
• Density: 1.08g/cm³
• Exact Mass: 303.20100
• Hazard Statements: C: Corrosive
• H-Bond Acceptor: 4
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 73183-34-3
• 364793-86-2

• 364794-79-6
• 364794-80-9

Reference: [1] Patent: US2002/26052, 2002, A1,

Upstream Synthesis Route 2

• 110-91-8
• 443776-76-9

• 364794-80-9

Reference: [1] Organic Letters, 2013, vol. 15, # 18, p. 4850 - 4853

Upstream Synthesis Route 3

• 110-91-8
• 214360-74-4

• 364794-80-9

Reference: [1] ACS Combinatorial Science, 2011, vol. 13, # 1, p. 24 - 31

Upstream Synthesis Route 4

• 73183-34-3
• 364793-82-8

• 364794-80-9

Reference: [1]European Journal of Medicinal Chemistry,2019,vol. 179,p. 449 - 469
[2]Bioorganic and Medicinal Chemistry Letters,2002,vol. 12,p. 2989 - 2992
[3]Journal of Medicinal Chemistry,2008,vol. 51,p. 196 - 218
[4]Journal of Medicinal Chemistry,2013,vol. 56,p. 3820 - 3832