Tetrahydrofurfuryl alcohol

• CAS: 97-99-4
• Catalog Number: ACM97994-2
• Category: Solvents
• Molecular Weight: 102.13
• Molecular Formula: C5H10O2
• Synonyms: NSC 15434, Tetrahydro-2-furanmethanol
• IUPAC Name: (oxolan-2-yl)methanol
• Canonical SMILES: OCC1CCCO1
• InChI: 1S/C5H10O2/c6-4-5-2-1-3-7-5/h5-6H,1-4H2
• InChI Key: BSYVTEYKTMYBMK-UHFFFAOYNA-N
• Boiling Point: 176.8±8.0 °C at 760 mmHg
• Melting Point: -80ºC
• Flash Point: 83.9±0.0 °C
• Density: 1.0±0.1 g/cm³
• Solubility: acetone: miscible(lit.); alcohol: miscible(lit.); benzene: miscible(lit.); chloroform: miscible(lit.); diethyl ether: miscible(lit.); water: miscible(lit.)
• Application: Tetrahydrofurfuryl alcohol undergoes chemoselective hydrogenolysis catalyzed by Rh/SiO2 modified with ReOx species to yield 1,5-pentanediol. It undergoes lanthanum-mediated Michael-type addition reaction with maleate to form alkoxybutanedioic acid.; Tetrahydrofurfuryl alcohol was used as a refractive-index matching solvent to ensure hard sphere suspension of silica particles for rheological measurements.
• Beilstein: 102723
• EC Number: 202-625-6
• Exact Mass: 102.068077
• Form: Clear liquid
• Hazard Codes: Xi:Irritant
• Hazard Statements: H319-H360Df
• LogP: -0.39
• MDL Number: MFCD00005372
• NACRES: NA.22
• PSA: 29.46
• PubChem ID: 24851135
• Refractive Index: 1.447
• Vapor Density: 3.52 (vs air)
• Vapor Pressure: 0.3±0.7 mmHg at 25°C
• WGK Germany: 2

Custom Q&A

What is the molecular formula of tetrahydrofurfuryl alcohol?

The molecular formula of tetrahydrofurfuryl alcohol is C5H10O2.

What is the weight of one mole of tetrahydrofurfuryl alcohol?

One mole of tetrahydrofurfuryl alcohol has a weight of 102.13 g/mol.

How is tetrahydrofurfuryl alcohol described physically?

Tetrahydrofurfuryl alcohol is described as a clear colorless liquid with a mild odor. Its vapors are heavier than air.

What is the IUPAC name of tetrahydrofurfuryl alcohol?

The IUPAC name of tetrahydrofurfuryl alcohol is oxolan-2-ylmethanol.

What is the InChIKey of tetrahydrofurfuryl alcohol?

The InChIKey of tetrahydrofurfuryl alcohol is BSYVTEYKTMYBMK-UHFFFAOYSA-N.

What is the Canonical SMILES representation of tetrahydrofurfuryl alcohol?

The Canonical SMILES representation of tetrahydrofurfuryl alcohol is C1CC(OC1)CO.

What is the CAS number of tetrahydrofurfuryl alcohol?

The CAS number of tetrahydrofurfuryl alcohol is 97-99-4.

Does tetrahydrofurfuryl alcohol have any synonyms?

Yes, tetrahydrofurfuryl alcohol has synonyms such as (Tetrahydrofuran-2-yl)methanol, Tetrahydro-2-furanmethanol, and oxolan-2-ylmethanol.

Is tetrahydrofurfuryl alcohol a natural product?

Yes, tetrahydrofurfuryl alcohol is a natural product found in Mangifera indica.

What is the XLogP3-AA value of tetrahydrofurfuryl alcohol?

The XLogP3-AA value of tetrahydrofurfuryl alcohol is -0.1.

Synthetic Use

Upstream Synthesis Route 1

• 14697-46-2

• 19752-84-2
• 97-99-4

Reference: [1] Green Chemistry, 2009, vol. 11, # 1, p. 48 - 52
[2] Journal of Chemical and Engineering Data, 2009, vol. 54, # 9, p. 2666 - 2668

Upstream Synthesis Route 2

• 6790-38-1

• 19752-84-2
• 97-99-4
• 21915-56-0

Reference: [1] Heterocycles, 1982, vol. 18, p. 281 - 284

Upstream Synthesis Route 3

• 6790-38-1

• 19752-84-2
• 97-99-4
• 21915-56-0

Reference: [1]Heterocycles,1982,vol. 18,p. 281 - 284

Upstream Synthesis Route 4

• 87392-05-0

• 97-99-4

Reference: [1]European Journal of Organic Chemistry,2001,p. 4537 - 4542

Downstream Synthesis Route 1

• 97-99-4

• 33414-62-9

Reference: [1] Journal of Organic Chemistry, 2004, vol. 69, # 4, p. 1331 - 1336
[2] Patent: WO2016/19228, 2016, A1,

* For details of the synthesis route, please refer to the original source to ensure accuracy.