tert-Butyl 5-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate

• CAS: 215184-78-4
• Catalog Number: ACM215184784
• Category: Other Products
• Molecular Weight: 312.202220 [g/mol]
• Molecular Formula: C₁₄H₁₈BrNO₂
• Synonyms: 215184-78-4, tert-Butyl 5-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate, tert-butyl 5-bromo-3,4-dihydro-1H-isoquinoline-2-carboxylate, 5-BROMO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER, SureCN2119725, AGN-PC-01U7R6, CTK4E7028, MolPort-007-650-675, ANW-49645, AKOS001836528, AG-E-57696, MCULE-4149498597, AK-31736, BR-31736, KB-61286, W4464, A26730, 2(1H)-Isoquinolinecarboxylicacid, 5-bromo-3,4-dihydro-, 1,1-dimethylethyl ester, 5-Bromo-3,4-dihydro-1H-isoquinoline-2-carboxylicacid tert-butyl ester; tert-Butyl5-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate
• IUPAC Name: tert-butyl 5-bromo-3,4-dihydro-1H-isoquinoline-2-carboxylate
• InChI Key: YSAAGRAKROVFRY-UHFFFAOYSA-N
• Boiling Point: 382.4ºC at 760 mmHg
• Flash Point: 185ºC
• Density: 1.353g/cm³
• Exact Mass: 311.05200
• H-Bond Acceptor: 2
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 24424-99-5
• 1258856-73-3

• 215184-78-4

Reference: [1] Patent: WO2010/146105, 2010, A1, . Location in patent: Page/Page column 86

Upstream Synthesis Route 2

• 24424-99-5

• 215184-78-4

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 18, p. 3050 - 3056

Upstream Synthesis Route 3

• 24424-99-5
• 81237-69-6

• 215184-78-4

Reference: [1] Patent: WO2018/83136, 2018, A1, . Location in patent: Page/Page column 62

Downstream Synthesis Route 1

• 1530-89-8
• 215184-78-4

• 441065-62-9

Reference: [1]Patent: US2003/69230,2003,A1

Downstream Synthesis Route 2

• 4394-85-8
• 215184-78-4

• 441065-33-4

Reference: [1]Patent: US2003/69230,2003,A1

* For details of the synthesis route, please refer to the original source to ensure accuracy.