TD52

• CAS: 1798328-24-1
• Catalog Number: ACM1798328241
• Category: Inhibitors
• Molecular Weight: 360.42
• Molecular Formula: C24H16N4
• Description: TD52 is an erlotinib derivative. TD52 is a putative inhibitor of CIP2A that exhibits potent antitumor efficacy on HCC and TNBC cells. TD52 induces apoptosis through downregulation of CIP2A (Cancerous inhibitor of protein phosphatase 2A) in HCC, NSCLC and TNBC cells.
• Synonyms: TD52; TD-52; TD 52; erlotinib derivative; erlotinib analogue
• IUPAC Name: N2,N3-bis(3-ethynylphenyl)quinoxaline-2,3-diamine
• Canonical SMILES: C#CC1=CC=CC(NC2=NC3=CC=CC=C3N=C2NC4=CC=CC(C#C)=C4)=C1
• InChI: InChI=1S/C24H16N4/c1-3-17-9-7-11-19(15-17)25-23-24(26-20-12-8-10-18(4-2)16-20)28-22-14-6-5-13-21(22)27-23/h1-2,5-16H,(H,25,27)(H,26,28)
• InChI Key: SCUPZFSEJFWQIS-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: To be determined
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: To be determined
• Elemental Analysis: C, 79.98; H, 4.47; N, 15.55
• Exact Mass: 360.1375
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).