TBTA, Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl] amine

• CAS: 510758-28-8
• Catalog Number: ACM510758288-4
• Category: Amino Acids
• Molecular Weight: 530.6
• Molecular Formula: C30H30N10
• Description: TBTA is a chemical compound that is also known as tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine. It is a highly effective ligand that is used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. This compound was first introduced in 2006 by Himo et al. as a novel ligand for the CuAAC reaction. Since then, TBTA has been extensively used in a wide range of scientific applications, from drug discovery to material science.
• Synonyms: Tris(benzyltriazolylmethyl)amine, tris-benzyltriazolylmethylamine, Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine, TBTA
• IUPAC Name: 1-(1-benzyltriazol-4-yl)-N,N-bis[(1-benzyltriazol-4-yl)methyl]methanamine
• Canonical SMILES: C1=CC=C(C=C1)CN2C=C(N=N2)CN(CC3=CN(N=N3)CC4=CC=CC=C4)CC5=CN(N=N5)CC6=CC=CC=C6
• InChI: 1S/C30H30N10/c1-4-10-25(11-5-1)16-38-22-28(31-34-38)19-37(20-29-23-39(35-32-29)17-26-12-6-2-7-13-26)21-30-24-40(36-33-30)18-27-14-8-3-9-15-27/h1-15,22-24H,16-21H2
• InChI Key: WKGZJBVXZWCZQC-UHFFFAOYSA-N
• Boiling Point: 762.4±70.0 ℃at 760 mmHg
• Melting Point: 132-143℃
• Flash Point: 414.9±35.7 ℃
• Density: 1.3±0.1 g/cm³
• Application: TBTA has many applications in scientific experiments, including drug discovery, bioconjugation, materials science, and nanotechnology. In drug discovery, TBTA is used to synthesize new drug candidates by coupling small molecules to larger molecules. In bioconjugation, TBTA is used to attach biomolecules to surfaces or other biomolecules. In materials science and nanotechnology, TBTA is used to synthesize nanomaterials and to modify their surfaces.
• Color: white
• Exact Mass: 530.265503
• Form: solid
• LogP: 3.18
• PSA: 95.37
• Refractive Index: 1.696
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, Azide and Alkyne containing Amino Acids
• Vapor Pressure: 0.0±2.6 mmHg at 25℃