T-Butyldimethylchlorosilane

• CAS: 18162-48-6
• Catalog Number: ACM18162486
• Category: Halosilane
• Molecular Weight: 150.72 g/mol
• Molecular Formula: C6H15ClSi
• Synonyms: TBDMSCL; tert-Butyldimethylsilylchloride; Tert-Butyldimethylchlorosilane; tert-Butyl(chloro)dimethylsilane; tert-Butyl(chloro)dimethylsilane,tert-Butyldimethylchlorosilane,TBDMSCl; TBDMCl; tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent]; TBSCL; BDCS; CB2790; tert-Butylchlorodimethylsilane; tbdmschloride; SILANE TBM2; TBUME2SI-CL; TBDMCS; tert-Butyldimethylsilyl chloride; TBDMSCI; tert-Butyldim
• IUPAC Name: tert-butyl-chloro-dimethylsilane
• Canonical SMILES: CC(C)(C)[Si](C)(C)Cl
• InChI Key: BCNZYOJHNLTNEZ-UHFFFAOYSA-N
• Boiling Point: 124-6 °C
• Melting Point: 86-89 °C
• Flash Point: 22 °C
• Density: 0.879 g/mL
• Appearance: Transparent liquid
• Application: T-Butyldimethylchlorosilane serves a critical role in organic synthesis as a protective agent for hydroxyl groups making it invaluable in the creation of various compounds including prostaglandins Its applications extend to aiding in the synthesis of hypolipidemic drugs such as lovastatin and simvastatin As a versatile reagent it safeguards amines amides and alcohols and plays a crucial part in forming isoxazolines N-oxides from alpha-bromonitroalkanes This sterically hindered organosilicon compound is employed broadly in the pharmaceutical industry for synthesizing innovative drugs It acts as a protecting group for hydroxyls in ribonucleosides synthesis and serves additional roles as an oxidant and decyanide Furthermore T-Butyldimethylchlorosilane effectively traps anions such as lithio α-phenylthiocyclopropane to yield di-TBDMS-thiophene and efficiently captures lithium anions of primary and secondary nitriles to produce CN-disilyl- and N-silylketenimines It has also been leveraged to prepare silyl stannanes by trapping tin anions which when used with alkynes and catalytic tetrakis(triphenylphosphine)palladium(0) can produce cis-silyl stannylalkenes with high yield
• EC Number: 242-042-4
• Exact Mass: 150.06300
• Hazard Statements: C:Corrosive
• Packaging: 10 g; 100 g
• Packing Group: III
• Safety Description: S16-S25-S36/37/39-S45
• Stability: Stable under normal temperatures and pressures.
• WGK Germany: 2

Custom Q&A

What is the molecular formula of t-Butyldimethylchlorosilane?

The molecular formula of t-Butyldimethylchlorosilane is C6H15ClSi.

What is the molecular weight of t-Butyldimethylchlorosilane?

The molecular weight of t-Butyldimethylchlorosilane is 150.72 g/mol.

What are the synonyms for t-Butyldimethylchlorosilane?

The synonyms for t-Butyldimethylchlorosilane include tert-Butyldimethylsilyl chloride, tert-Butylchlorodimethylsilane, and t-Butyldimethylchlorosilane.

What is the IUPAC name of t-Butyldimethylchlorosilane?

The IUPAC name of t-Butyldimethylchlorosilane is tert-butyl-chloro-dimethylsilane.

What is the InChIKey of t-Butyldimethylchlorosilane?

The InChIKey of t-Butyldimethylchlorosilane is BCNZYOJHNLTNEZ-UHFFFAOYSA-N.

What is the CAS number of t-Butyldimethylchlorosilane?

The CAS number of t-Butyldimethylchlorosilane is 18162-48-6.

How many hydrogen bond donor counts does t-Butyldimethylchlorosilane have?

t-Butyldimethylchlorosilane has 0 hydrogen bond donor counts.

How many rotatable bond counts does t-Butyldimethylchlorosilane have?

t-Butyldimethylchlorosilane has 1 rotatable bond count.

What is the exact mass of t-Butyldimethylchlorosilane?

The exact mass of t-Butyldimethylchlorosilane is 150.0631547 g/mol.

How many heavy atom counts does t-Butyldimethylchlorosilane have?

t-Butyldimethylchlorosilane has 8 heavy atom counts.