Sennidin A

• CAS: 641-12-3
• Catalog Number: ACM641123-1
• Category: Inhibitors
• Molecular Weight: 538.46
• Molecular Formula: C30H18O10
• Description: Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation.
• Synonyms: (9R, 9'R) - Rel- (+) -9, 9', 10, 10'- Tetrahydro- 4, 4', 5, 5'- tetrahydroxy- 10, 10'- dioxo- [9, 9'- Bianthracene] - 2, 2'- dicarboxylic acid
• IUPAC Name: 9-(2-carboxy-4,5-dihydroxy-10-oxo-9H-anthracen-9-yl)-4,5-dihydroxy-10-oxo-9H-anthracene-2-carboxylic acid
• Canonical SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2C4C5=C(C(=CC=C5)O)C(=O)C6=C4C=C(C=C6O)C(=O)O)C=C(C=C3O)C(=O)O
• InChI: InChI=1S/C30H18O10/c31-17-5-1-3-13-21(15-7-11(29(37)38)9-19(33)25(15)27(35)23(13)17)22-14-4-2-6-18(32)24(14)28(36)26-16(22)8-12(30(39)40)10-20(26)34/h1-10,21-22,31-34H,(H,37,38)(H,39,40)
• InChI Key: JPMRHWLJLNKRTJ-UHFFFAOYSA-N
• Appearance: Solid