(S,S)-2,2'-METHYLENEBIS(4-TERT-BUTYL-2-OXAZOLINE)

• CAS: 132098-54-5
• Catalog Number: ACM132098545
• Category: Other Products
• Molecular Weight: 266.38
• Molecular Formula: C₁₅H₂₆N₂O₂
• Synonyms: (S,S)-2,2-Methylenebis(4-tert-butyl-2-oxazoline), 132098-54-5, AC1LELKI, Maybridge4_001842, SureCN918989, 405965_ALDRICH, CTK0H0057, MolPort-002-904-423, HMS1526D16, CCG-43814, ZINC00056887, AG-D-64637, NCGC00177200-01, 2,2-Methylenebis[(4S)-4-tert-butyl-2-oxazoline, SR-01000633701-1, BRD-K22575383-001-01-5, 2,2 inverted exclamation marka-Methylenebis[(4S)-4-tert-butyl-2-oxazoline], (S,S)-2,2 inverted exclamation marka-Methylenebis(4-tert-butyl-2-oxazoline), (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole
• IUPAC Name: (4S)-4-tert-butyl-2-[[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]methyl]-4,5-dihydro-1,3-oxazole
• Canonical SMILES: CC(C)(C)C1COC(=N1)CC2=NC(CO2)C(C)(C)C
• InChI Key: WCCCBUXURHZPQL-GHMZBOCLSA-N
• Boiling Point: 328.8ºC at 760 mmHg
• Melting Point: 51-53ºC(lit.)
• Flash Point: 124.8ºC
• Density: 1.08g/cm³
• Exact Mass: 266.19900
• Hazard Statements: Xi
• H-Bond Acceptor: 4
• H-Bond Donor: 0
• Safety Description: S26

Synthetic Use

Upstream Synthesis Route 1

• 112245-13-3
• 10344-69-1

• 132098-54-5

Reference: [1] Advanced Synthesis and Catalysis, 2016, vol. 358, # 6, p. 864 - 868
[2] Journal of Organic Chemistry, 2000, vol. 65, # 18, p. 5875 - 5878
[3] Advanced Synthesis and Catalysis, 2008, vol. 350, # 7-8, p. 1023 - 1045
[4] Journal of the American Chemical Society, 2017, vol. 139, # 25, p. 8420 - 8423
[5] Helvetica Chimica Acta, 1991, vol. 74, # 1, p. 232 - 240

Upstream Synthesis Route 2

• 133463-95-3

• 132098-54-5
• 133464-00-3

Reference: [1] Helvetica Chimica Acta, 1991, vol. 74, # 1, p. 232 - 240

Upstream Synthesis Route 3

• 133464-00-3

• 132098-54-5

Reference: [1] Helvetica Chimica Acta, 1991, vol. 74, # 1, p. 232 - 240

Downstream Synthesis Route 1

• 628-77-3
• 132098-54-5

• 298693-04-6

Reference: [1]Denmark, Scott E.; Stiff, Cory M.
[Journal of Organic Chemistry, 2000, vol. 65, # 18, p. 5875 - 5878]
[2]Denmark, Scott E.; Nakajima, Noriyuki; Stiff, Cory M.; Nicaise, Olivier J.-C.; Kranz, Michael
[Advanced Synthesis and Catalysis, 2008, vol. 350, # 7-8, p. 1023 - 1045]

Downstream Synthesis Route 2

• 132098-54-5
• 100-44-7

• 319489-90-2

Reference: [1]Burguete; Fraile; Garcia; Garcia-Verdugo; Herrerias; Luis; Mayoral
[Journal of Organic Chemistry, 2001, vol. 66, # 26, p. 8893 - 8901]
[2]Diez-Barra, Enrique; Fraile, Jose M.; Garcia, Jose I.; Garcia-Verdugo, Eduardo; Herrerias, Clara I.; Luis, Santiago V.; Mayoral, Jose A.; Sanchez-Verdu, Prado; Tolosa, Juan
[Tetrahedron Asymmetry, 2003, vol. 14, # 7, p. 773 - 778]
[3]Burguete, M. Isabel; Fraile, Jose M.; Garcia, Jose I.; Garcia-Verdugo, Eduardo; Luis, Santiago V.; Mayoral, Jose A.
[Organic Letters, 2000, vol. 2, # 24, p. 3905 - 3908]

* For details of the synthesis route, please refer to the original source to ensure accuracy.