Roflumilast-d3

CAS

1189992-00-4

Catalog Number

ACM1189992004

Category

Inhibitors

Molecular Weight

406.23

Molecular Formula

C₁₇H₁₁D₃Cl₂F₂N₂O₃

MSDS COA Spec Sheet

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Specification

Description

Roflumilast-d3 is deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.

Synonyms

3-(Cyclopropylmethoxy-d3)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d3; BY 217-d3; BYK 20869-d3;

Canonical SMILES

[2H]C1(CC1)C([2H])([2H])OC2=C(C=CC(C(NC3=C(Cl)C=NC=C3Cl)=O)=C2)OC(F)F

Appearance

Crystallin Solid

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Can be shipped at room temperature, where not in use may vary.