(R)-tert-Butyl 3-(methylsulfonyloxy)pyrrolidine-1-carboxylate

• CAS: 127423-61-4
• Catalog Number: ACM127423614
• Category: Other Products
• Molecular Weight: 265.328
• Molecular Formula: C₁₀H₁₉NO₅S
• Synonyms: (R)-1-Boc-3-methanesulfonyloxypyrrolidine, 127423-61-4, (R)-3-Methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester, AC1Q1MXA, (R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected, PYR162, CTK7G2629, MolPort-000-001-565, AB3122, ZINC04203037, AKOS015838270, AKOS015897544, AB30455, AG-A-07164, AK144243, FT-0687383, ST51053595, A-6340, B50670, I09-1025
• IUPAC Name: tert-butyl (3R)-3-methylsulfonyloxypyrrolidine-1-carboxylate
• Canonical SMILES: CC(C)(C)OC(=O)N1CCC(C1)OS(=O)(=O)C
• InChI Key: KWQRKOSMSFLBTJ-MRVPVSSYSA-N
• Exact Mass: 265.09800
• H-Bond Acceptor: 5
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 83220-73-9
• 124-63-0

• 127423-61-4

Reference: [1] Patent: WO2010/45542, 2010, A2, . Location in patent: Page/Page column 73

Upstream Synthesis Route 2

• 124-63-0
• 101469-92-5

• 127423-61-4

Reference: [1] Patent: WO2007/93363, 2007, A1, . Location in patent: Page/Page column 88

Upstream Synthesis Route 3

• 101385-90-4

• 127423-61-4

Reference: [1] Journal of Medicinal Chemistry, 1999, vol. 42, # 4, p. 677 - 690
[2] Journal of Medicinal Chemistry, 1997, vol. 40, # 22, p. 3497 - 3500

Upstream Synthesis Route 4

• 109431-87-0
• 124-63-0

• 127423-61-4

Reference: [1]Patent: WO2010/45542,2010,A2 .Location in patent: Page/Page column 73

Upstream Synthesis Route 5

• 132945-75-6

• 127423-61-4

Reference: [1]Nucleosides, nucleotides and nucleic acids,2005,vol. 24,p. 805 - 808
[2]Tetrahedron,2006,vol. 62,p. 5763 - 5774

Upstream Synthesis Route 6

• 101930-07-8

• 127423-61-4

Reference: [1]Sternfeld, Francine; Guiblin, Alexander R.; Jelley, Richard A.; Matassa, Victor G.; Reeve, Austin J.; Hunt, Peter A.; Beer, Margaret S.; Heald, Anne; Stanton, Josephine A.; Sohal, Bindi; Watt, Alan P.; Street, Leslie J.
[Journal of Medicinal Chemistry, 1999, vol. 42, # 4, p. 677 - 690]
[2]Castro; Street; Guiblin; Jelley; Russell; Sternfeld; Beer; Stanton; Matassa
[Journal of Medicinal Chemistry, 1997, vol. 40, # 22, p. 3497 - 3500]