(R)-tert-Butyl 3-(bromomethyl)piperidine-1-carboxylate

• CAS: 1002359-91-2
• Catalog Number: ACM1002359912
• Category: Other Products
• Molecular Weight: 278.19
• Molecular Formula: C₁₁H₂₀BrNO₂
• Synonyms: (R)-TERT-BUTYL 3-(BROMOMETHYL)PIPERIDINE-1-CARBOXYLATE, 1002359-91-2, SureCN1974493, CTK3J8657, ZINC02527642, AG-D-04713, PB31551, AK109926, (R)-1-BOC-3-BROMOMETHYLPIPERIDINE, KB-210488, (R)-3-BROMOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, 1,1-DIMETHYLETHYL (3R)-3-(BROMOMETHYL)-1-PIPERIDINECARBOXYLATE
• IUPAC Name: tert-butyl (3R)-3-(bromomethyl)piperidine-1-carboxylate
• Canonical SMILES: CC(C)(C)OC(=O)N1CCCC(C1)CBr
• InChI Key: MGGZYACWICDRRD-VIFPVBQESA-N
• Exact Mass: 277.06800
• H-Bond Acceptor: 2
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 116574-71-1

• 1002359-91-2

Reference: [1]Journal of Medicinal Chemistry,2008,vol. 51,p. 5663 - 5679
[2]Patent: WO2010/18134,2010,A1 .Location in patent: Page/Page column 58

Downstream Synthesis Route 1

• 842149-46-6
• 1002359-91-2

• 1052112-34-1

Reference: [1]Location in patent: experimental part
Heerding, Dirk A.; Rhodes, Nelson; Leber, Jack D.; Clark, Tammy J.; Keenan, Richard M.; Lafrance, Louis V.; Li, Mei; Safonov, Igor G.; Takata, Dennis T.; Venslavsky, Joseph W.; Yamashita, Dennis S.; Choudhry, Anthony E.; Copeland, Robert A.; Lai, Zhihong; Schaber, Michael D.; Tummino, Peter J.; Strum, Susan L.; Wood, Edgar R.; Duckett, Derek R.; Eberwein, Derek; Knick, Victoria B.; Lansing, Timothy J.; McConnell, Randy T.; Zhang, ShuYun; Minthorn, Elisabeth A.; Concha, Nestor O.; Warren, Gregory L.; Kumar, Rakesh
[Journal of Medicinal Chemistry, 2008, vol. 51, # 18, p. 5663 - 5679]

* For details of the synthesis route, please refer to the original source to ensure accuracy.