Pyrazoloacridine

• CAS: 99009-20-8
• Catalog Number: ACM99009208
• Category: Inhibitors
• Molecular Weight: 367.40174;g/mol
• Molecular Formula: C19H21N5O3
• Description: Pyrazoloacridine (NSC 366140), an intercalating agent with anti-cancer activity, inhibits the activity of topoisomerases 1 and 2. Pyrazoloacridine (NSC 366140) exhibits an IC50 of 1.25 μM in K562 myeloid leukemia cells for 24 h treatment.
• Synonyms: Fluoren-9-yl-methyl-aether; 9-Methoxy-fluoren; 9-methoxyfluorene; fluoren-9-yl-methyl ether; 9-Methoxyellipticine; 9-methoxy-9H-fluorene; methoxyellipticine
• IUPAC Name: 3-(9-Methoxy-5-nitropyrazolo[3,4,5-kl]acridin-2(1H)-yl)-N,N-dimet hyl-...
• Canonical SMILES: CN(C)CCCN1C2=C3C(=C4C=C(C=CC4=NC3=C(C=C2)[N+](=O)[O-])OC)N1
• InChI Key: HVRZAFDJOWIDMM-UHFFFAOYSA-N
• Boiling Point: 595.6ºC at 760 mmHg
• Flash Point: 314ºC
• Density: 1.314g/cm³
• Appearance: Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Exact Mass: 367.16400
• Shipping: Can be shipped at room temperature, where not in use may vary.