Povidone iodine

• CAS: 25655-41-8
• Catalog Number: ACM25655418
• Category: Polymer/Macromolecule
• Molecular Weight: 141.2108
• Molecular Formula: C6H9I2NO
• Description: Povidone-iodine (PVP-I), brand name Wokadine, Pyodine, and Betadine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than tincture of iodine.Human clinical trials showed the product to be superior to other iodine formulations.Betadine was immediately marketed, and has since become the universally preferred iodine antiseptic.It is on the WHO Model List of Essential Medicines, the most important products needed in a basic health system.
• Synonyms: Povidone iodine(PVPI)
• Melting Point: 300ºC
• Flash Point: 93.9ºC
• Appearance: A red-brown crystalline powder
• Application: Cooling water systems, oilfield water treatment
• Storage: Storage for ten months in room shady and dry place.
• HS Code: 3808940010
• LogP: 2.46160
• Loss On Drying: 8.0%
• MDL Number: MFCD00084483
• pH: 1.5-5.0
• Physical State: White powder
• PSA: 2.31
• Stability: Stable under normal temperatures and pressures.
• Storage Conditions: Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Store in air tight containers.
• Vapor Pressure: 0.132mmHg at 25°C

Custom Q&A

What is the molecular formula of povidone iodine?

The molecular formula of povidone iodine is C6H9I2NO.

What is the molecular weight of povidone iodine?

The molecular weight of povidone iodine is 364.95 g/mol.

What is the synonym for povidone iodine?

The synonym for povidone iodine is Betadine.

What is the percentage of available iodine in povidone iodine?

Povidone iodine contains from 9.0% to 12.0% available iodine.

Who discovered the complex of povidone iodine?

The complex of povidone iodine was discovered by H. A. Shelanski and M. V. Shelanski at the Industrial Toxicology Laboratories in Philadelphia.

What is the mechanism of action of povidone iodine?

Povidone iodine slowly releases iodine, which kills cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds.

What range of microorganisms does povidone iodine have activity against?

Povidone iodine exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses.

What is the common use of povidone iodine in surgery?

Povidone iodine is used as a topical antiseptic in surgery and for skin and mucous membrane infections.

Can iodine in povidone iodine be radiolabeled?

Yes, the iodine in povidone iodine can be radiolabeled for research purposes.

What is the ICSC number of povidone iodine?

The ICSC number of povidone iodine is 1471.