Polyglycolide

CAS
26124-68-5
Catalog Number
ACM26124685-2
Category
Other Products
Molecular Weight
76.05g/mol
Molecular Formula
(C2H4O3)n

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Specification

Description
Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.
Synonyms
PGA, Poly(glycolic acid)
IUPAC Name
2-hydroxyacetic acid
Canonical SMILES
OCC(O)=O
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI Key
AEMRFAOFKBGASW-UHFFFAOYSA-N
Boiling Point
100 °C
Melting Point
79.5 °C;78-80 °C (alpha-modification); 63 °C (beta-modification, metastable);75-80°C;80 °C
Density
1.53 g/mL at 25 °C (lit.)
Solubility
In water, 1X10+6 mg/L at 25 °C (est);Soluble in ethanol, ethyl ether;Soluble in methanol, acetone, acetic acid;Solubility in water: very good
Application
Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.
Color/Form
Colorless, translucent solid;Solid glycolic acid forms colorless, monoclinic, prismatic crystals.;Orthorhombic needles from water; leaves from diethyl ether
Complexity
40.2
Corrosivity
Corrosive
Covalently-Bonded Unit Count
1
Decomposition
Hazardous decomposition products formed under fire conditions. - Carbon oxides;When heated to decomposition it emits acrid smoke and irritating fumes.;100 °C
EC Number
201-180-5;217-693-2;247-326-1
Exact Mass
76.016044g/mol
Features And Benefits
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.
Formal Charge
0
H-Bond Acceptor
3
H-Bond Donor
2
Heavy Atom Count
5
ICSC Number
1537
LogP
-1.11 (LogP);log Kow = -1.11;-1.11;-1.11
MDL Number
MFCD00148011
Monoisotopic Mass
76.016044g/mol
NACRES
NA.23
NSC Number
166
Odor
Odorless
Other Experimental
BP: decomposes;MP: 79.5 °C;Hygroscopic;Heat of combustion: 697.1kJ/mole; heat of solution: -11.5 kJ/mole;Light, straw-colored lliquid, odor like burnt sugar; density: 1.27; mp: 10 °C /Commercial 70% solution/;When heated to decomposition it emits acrid smoke and irritating fumes.;Henry's Law constant = 8.5X10-8 atm-cu m/mol at 25 °C (est);Hydroxyl radical reaction rate constant = 3.11X10-12 cu cm/molecule-sec at 25 °C (est)
Packaging
1, 5, 10 g in glass bottle
PubChem ID
24869373
Quality Level
100
Rotatable Bond Count
1
RTECS Number
MC5250000
Stability
Stable under recommended storage conditions.
Storage Temperature
2-8°C
UNII
0WT12SX38S
UN Number
3261
Vapor Density
Relative vapor density (air = 1): 2.6
Vapor Pressure
0.02 mmHg;2.0X10-2 mm Hg at 25 °C (extrapolated)
XLogP3
-1.1
What is the molecular weight of Polyglycolide?

The molecular weight of Polyglycolide is 76.05g/mol.

How is high molecular weight polyglycolide (PGA) prepared?

High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.

What is another name for Polyglycolide?

Another name for Polyglycolide is Poly(glycolic acid) or PGA.

What is the IUPAC name for Polyglycolide?

The IUPAC name for Polyglycolide is 2-hydroxyacetic acid.

What is the boiling point of Polyglycolide?

The boiling point of Polyglycolide is 100 °C.

What is the solubility of Polyglycolide in water?

Polyglycolide is very soluble in water.

What are some applications of Polyglycolide?

Polyglycolide (PGA) may be used to prepare a biodegradable copolymer for implantations, fabricate biopolymer/carbon nanotube composites, and fabricate modified porous PGA scaffolds.

What are some features and benefits of Polyglycolide?

Some features and benefits of Polyglycolide include being non-toxic, biodegradable in soil, having broad miscibility, mechanical compatibility with many polymers, and good adhesion to a broad spectrum of substrates.

How is Polyglycolide packaged?

Polyglycolide is typically packaged in 1, 5, or 10 g glass bottles.

What is the storage temperature recommended for Polyglycolide?

The recommended storage temperature for Polyglycolide is 2-8°C.

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