PHTHALAZIN-5-AMINE

• CAS: 102072-84-4
• Catalog Number: ACM102072844
• Category: Other Products
• Molecular Weight: 145.16
• Molecular Formula: C8H7N3
• Synonyms: 5-AMINO-PHTHALAZINE;PHTHALAZIN-5-AMINE;Quinoxalin-5-ylamine
• IUPAC Name: phthalazin-5-amine
• Canonical SMILES: C1=CC2=CN=NC=C2C(=C1)N
• InChI Key: IXASUUHIFCTEJK-UHFFFAOYSA-N
• Boiling Point: 423.2ºC at 760 mmHg
• Flash Point: 239.3ºC
• Density: 1.292g/cm³
• Exact Mass: 145.06400
• H-Bond Acceptor: 3
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 89898-86-2

• 102072-84-4

Reference: [1] Journal of Medicinal Chemistry, 1986, vol. 29, # 8, p. 1329 - 1340

Upstream Synthesis Route 2

• 253-52-1

• 102072-84-4

Reference: [1] Journal of Medicinal Chemistry, 2005, vol. 48, # 3, p. 744 - 752
[2] Journal of Medicinal Chemistry, 1986, vol. 29, # 8, p. 1329 - 1340
[3] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 1, p. 478 - 487
[4] Patent: US9522908, 2016, B2,

Upstream Synthesis Route 3

• 484-23-1

• 102072-84-4

Reference: [1] Journal of Medicinal Chemistry, 1986, vol. 29, # 8, p. 1329 - 1340

Upstream Synthesis Route 4

• 89898-86-2

• 102072-84-4

Reference: [1]Journal of Medicinal Chemistry,1986,vol. 29,p. 1329 - 1340

Downstream Synthesis Route 1

• 102072-84-4

• 147088-71-9

Reference: [1]Journal of the Chemical Society. Perkin transactions I,1993,p. 211 - 216
[2]Bioorganic and Medicinal Chemistry,2014,vol. 22,p. 478 - 487
[3]Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,p. 2577 - 2580
[4]Patent: US9522908,2016,B2 .Location in patent: Page/Page column 52

Downstream Synthesis Route 2

• 102072-84-4

• 102072-85-5

Reference: [1]Journal of Medicinal Chemistry,1986,vol. 29,p. 1329 - 1340

* For details of the synthesis route, please refer to the original source to ensure accuracy.