Phloretin

• CAS: 60-82-2
• Catalog Number: ACM60822
• Category: Material of Cosmetics
• Molecular Weight: 274.27
• Molecular Formula: C15H14O5
• Synonyms: Dihydronaringenin
• IUPAC Name: 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
• Canonical SMILES: C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
• InChI: InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
• InChI Key: VGEREEWJJVICBM-UHFFFAOYSA-N
• Boiling Point: 337.26 °C
• Melting Point: 260 °C
• Flash Point: 291.1 °C
• Density: 1.1827 g/cm³
• Solubility: Soluble in water
• Appearance: Powder
• Storage: 2-8 °C
• Active Content: 95%
• Assay: 0.99
• Complexity: 312
• Exact Mass: 274.08412354
• Monoisotopic Mass: 274.08412354
• Packaging: 1 kg
• Physical State: Solid
• pKa: 7.16±0.40(Predicted)
• Plant Origin: Branches and leaves from apple
• Refractive Index: 1.573-1.575
• Storage Conditions: 2-8°C
• Topological Polar Surface Area: 98 Ų

Custom Q&A

What is the CAS number for Phloretin?

The CAS number for Phloretin is 60-82-2.

What is the molecular weight of Phloretin?

The molecular weight of Phloretin is 274.26.

What is the molecular formula of Phloretin?

The molecular formula of Phloretin is C15H14O5.

What is the boiling point of Phloretin?

The boiling point of Phloretin is predicted to be 534.4 °C at 760 mmHg.

What is the melting point of Phloretin?

The melting point of Phloretin is 260-262°C.

What is the purity of Phloretin?

The purity of Phloretin is 98%.

What is the density of Phloretin?

The density of Phloretin is 1.429 g/cm³.

What is the appearance of Phloretin?

The appearance of Phloretin is a crystalline solid.

What are the typical applications of Phloretin?

Phloretin is typically used as an antioxidant.

What is the percentage of actives in Phloretin?

Phloretin contains 95% actives.

Synthetic Use

Upstream Synthesis Route 1

• 480-41-1

• 60-82-2

Reference: [1] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988, vol. 27, # 1-12, p. 899 - 901
[2] Synthetic Communications, 1989, vol. 19, # 1, 2, p. 119 - 124
[3] Angewandte Chemie - International Edition, 2014, vol. 53, # 5, p. 1439 - 1442[4] Angew. Chem., 2014, vol. 126, # 05, p. 1463 - 1466,4

Upstream Synthesis Route 2

• 108-73-6
• 17362-17-3

• 60-82-2

Reference: [1]Monatshefte fur Chemie,1929,vol. 53/54,p. 560

Downstream Synthesis Route 1

• 133-89-1
• 60-82-2

• 4192-90-9
• 60-81-1

Reference: [1] Organic Letters, 2014, vol. 16, # 18, p. 4874 - 4877

Downstream Synthesis Route 2

• 133-89-1
• 60-82-2

• 58-98-0
• 60-81-1

Reference: [1] Green Chemistry, 2014, vol. 16, # 9, p. 4417 - 4425

* For details of the synthesis route, please refer to the original source to ensure accuracy.