Structure

Pepstatin

CAS
26305-03-3
Catalog Number
ACM26305033
Category
Inhibitors
Molecular Weight
685.892
Molecular Formula
C34H63N5O9

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Specification

Description
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease.
Synonyms
ahpatininc;pepsininhibitors735a;procidins735a;PEPSTATIN;PEPSTATIN A;X-VAL-VAL-STATYL-ALA-STATIN;(3S,4S)-4-AMINO-3-HYDROXY-6-METHYL-HEPTANOIC ACID;AHMHA ISOVALERYL-L-VAL-L-VAL-AHMHA-L-ALA-STA
Melting Point
233 °C (dec.)(lit.)
Flash Point
557.1±34.3 °C
Density
1.1±0.1 g/cm3
Solubility
10% acetic acid in methanol: 1 mg/mL
Appearance
Solid
Storage
2-8°C
Exact Mass
685.462585
LogP
2.16
PSA
223.26000
Refractive Index
1.504
Safety Description
22-24/25
Shipping
Can be shipped at room temperature, where not in use may vary.
Source
Actinomycetes
Stability
Stable. Incompatible with strong bases, strong acids.
Vapor Pressure
0.0±0.6 mmHg at 25°C
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