150607-96-8 Purity
98%
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Specification
Chitosan pentasodium tripolyphosphate micro/nanoparticles were successfully prepared by ion gelation. The physicochemical properties of the particles can be optimized by changing the molar mass and deacetylation degree of chitosan and controlling charge ratio (R±). This method may be helpful for loading particles with active ingredients in the pharmaceutical and food fields to change the release profile and prolong the residence time of the molecules in the target.
Preparation of Chitosan Particles by Ionotropic
Chitosan solutions were 0.5% w/v prepared by emulsifying chitosan in a solution of 0.75% v/v acetic acid. It was stirred for 24 hours at 25°C, continuously with a magnetic stirring stirrer, until completely dissolved. It was pH-corrected to 4.8 at the final point with either 0.1 M sodium hydroxide or 0.1 M hydrochloric acid. Gradually, predetermined volumes of a 1.0% w/v pentasodium tripolyphosphate solution were added to the chitosan solution while maintaining mechanical stirring at 1,500 rpm. After each addition of pentasodium tripolyphosphate, the stirring lasted for another 15 minutes and then the average diameter, polydispersity index, and zeta potential were measured.
In this work, nanostructured sodium calcium tripolyphosphate and its peroxy solvates were synthesized using pentasodium triphosphate hexahydrate (Na5P3O10·6H2O) as raw materials. The high porosity structure and antibacterial properties of these materials make them promising for use as bioceramic materials.
Synthesis procedure
· Sodium calcium tripolyphosphate, represented as Na0.4Ca2.3P3O10·4H2O, was prepared by molar proportions of 2:1 in water with aqueous solution of CaCl2 and pentasodium triphosphate hexahydrate (Na5P3O10·6H2O). An alternative approach used added 0.3% gelatin solution to the Ca2+ solution before reaction.
· The peroxo derivatives of sodium calcium tripolyphosphate were prepared by hydrogen peroxide solutions of concentrations 49%, 66%, 73%, 90% and 96%. These peroxosolvates were obtained by three processes: (1) 4 mL H2O2 solution was added to 0.4 g of sodium calcium tripolyphosphate at 0°C for 2 hours, and the suspension was then passed through a glass filter at the same temperature, the solid washed with chilled ethanol and ether, and the ether was removed in a vacuum desiccator; (2) sodium calcium tripolyphosphate was suspended in 90% hydrogen peroxide at -18°C for about 1 month, and the solid was separated by the same process; and (3) a weighed sample ( 0.3 g) of the polyphosphate was placed in H2O2 vapor in anhydrone Mg(ClO4)2H2O at 5°C, until it had been saturated with hydrogen peroxide.
The molecular formula of Pentasodium triphosphate hexahydrate is H12Na5O16P3.
Some synonyms of Pentasodium triphosphate hexahydrate are 15091-98-2, T7Y93S4UXX, DTXSID9046605, and Sodium triphosphate hydrate (5:1:6).
The molecular weight of Pentasodium triphosphate hexahydrate is 475.96 g/mol.
The component compounds of Pentasodium triphosphate hexahydrate are Triphosphoric acid (CID 983), Sodium (CID 5360545), and Water (CID 962).
The IUPAC name of Pentasodium triphosphate hexahydrate is pentasodium;[oxido(phosphonatooxy)phosphoryl] phosphate;hexahydrate.
The InChI of Pentasodium triphosphate hexahydrate is InChI=1S/5Na.H5O10P3.6H2O/c;;;;;1-11(2,3)9-13(7,8)10-12(4,5)6;;;;;;/h;;;;;(H,7,8)(H2,1,2,3)(H2,4,5,6);6*1H2/q5*+1;;;;;;;/p-5.
The InChIKey of Pentasodium triphosphate hexahydrate is FGXJOKTYAQIFRP-UHFFFAOYSA-I.
The Canonical SMILES of Pentasodium triphosphate hexahydrate is O.O.O.O.O.O.[O-]P(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+].
The CAS number of Pentasodium triphosphate hexahydrate is 15091-98-2.
The hydrogen bond donor count of Pentasodium triphosphate hexahydrate is 6.