Pantoprazole

• CAS: 102625-70-7
• Catalog Number: ACM102625707
• Category: Inhibitors
• Molecular Weight: 383.37
• Molecular Formula: C16H15F2N3O4S
• Description: Pantoprazole, sold under the brand name Protonix among others, is used for short-term treatment of erosive esophagitis associated with gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger-Ellison Syndrome.Some common side effects of pantoprazole use in adults include: headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and joint pain (>2%). Use of pantoprazole for a long period of time may lead to chronic inflammation of stomach lining or atrophic gastritis, vitamin B-12 deficiency, and low magnesium.Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
• Synonyms: Pantoprazole acid
• IUPAC Name: 6-(Difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole
• Canonical SMILES: COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC
• InChI: InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)
• InChI Key: IQPSEEYGBUAQFF-UHFFFAOYSA-N
• Boiling Point: 586.9±60.0 °C
• Melting Point: 139-140 °C
• Flash Point: 308.7 °C
• Density: 1.51±0.1 g/cm³
• Appearance: Solid
• Storage: Inert atmosphere, store in freezer, under -20 °C
• Complexity: 490
• Exact Mass: 383.07513347
• Hazard Codes: Xn
• LogP: 3.75000
• Monoisotopic Mass: 383.07513347
• Physical Description: White to off white
• PSA: 15.54
• Refractive Index: 1.642
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Topological Polar Surface Area: 106 Ų
• Vapor Pressure: 9.37E-14mmHg at 25°C
• WGK Germany: 3