2'-O-Methylcytidine

• CAS: 2140-72-9
• Catalog Number: ACM2140729
• Category: Inhibitors
• Molecular Weight: 257.24
• Molecular Formula: C₁₀H₁₅N₃O₅
• Description: 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.
• Synonyms: 2-O-Methylcytidine, O-2-Methylcytidine, Cytidine, 2-O-methyl-, M0259_SIGMA, AIDS338901, CID301382, NSC178026, I07-0058, 2(1H)-Pyrimidinone, 4-amino-1-(2-O-methyl-.beta.-D-arabinofuranosyl)-, 2140-72-9, 35819-07-9
• IUPAC Name: 4-amino-1-[4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one
• Canonical SMILES: COC1C(C(OC1N2C=CC(=NC2=O)N)CO)O
• InChI Key: RFCQJGFZUQFYRF-UHFFFAOYSA-N
• Boiling Point: 506ºC at 760 mmHg
• Melting Point: 252-253ºC
• Flash Point: 259.8ºC
• Density: 1.68 g/cm³
• Appearance: Solid
• Storage: 4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light).
• Exact Mass: 257.10100
• Hazard Statements: Xi
• H-Bond Acceptor: 6
• H-Bond Donor: 3
• Safety Description: 26-36
• Shipping: Can be shipped at room temperature, where not in use may vary.