Nickel(II) Chloride Hydrate

• CAS: 69098-15-3
• Catalog Number: ACM69098153
• Category: Metal & Ceramic Materials
• Molecular Weight: 147.61
• Molecular Formula: Cl2H2NiO
• Synonyms: Nickel(II) chloride
• IUPAC Name: Dichloronickel;hydrate
• Canonical SMILES: O.Cl[Ni]Cl
• InChI: InChI=1S/2ClH.Ni.H₂O/h2*1H;1H2/q;+2;/p-2
• InChI Key: HGGYAQHDNDUIIQ-UHFFFAOYSA-L
• Melting Point: 1001 °C
• Solubility: Freely soluble in water
• Appearance: Green crystalline aggregates
• Application: Nickel(II) Chloride Hydrate serves as a versatile catalyst in various chemical processes, particularly in electroplating and organic reactions. It plays a significant role in the chemo-selective thioacetalization of aldehydes and, when combined with lithium aluminum hydride, functions as an efficient reducing agent for alkenes, alkynes, and organic halides, while also effectively cleaving N-O bonds and opening epoxides. Furthermore, this compound acts as a precursor in forming nickel-phosphine complexes, such as bis(triphenylphosphine)nickel(II) chloride, which are pivotal in facilitating reactions like alkyne trimerizations, carbonylations, and Suzuki-Miyaura cross-coupling, offering an alternative to palladium-based catalysts. Additionally, it is integral to the synthesis of the acetylacetonate complex of nickel, which is essential for producing the 1,5-cyclooctadiene complex used in organonickel chemistry. Nickel(II) Chloride Hydrate can also be utilized in forming the sandwich compound nickelocene through its dimethoxyethane complex, thereby further enhancing its applications in catalysis.
• Complexity: 2.8
• Covalently-Bonded Unit Count: 2
• EC Number: 231-743-0
• Exact Mass: 145.883612
• Formal Charge: 0
• H-Bond Acceptor: 1
• H-Bond Donor: 1
• Heavy Atom Count: 4
• MDL Number: MFCD00149808
• Monoisotopic Mass: 145.883612
• Physical State: Green crystals
• PubChem ID: 16212333
• Rotatable Bond Count: 0
• Topological Polar Surface Area: 1 Ų