NBD-Cl

• CAS: 10199-89-0
• Catalog Number: ACM10199890-1
• Category: Other Fluorophores
• Molecular Weight: 199.55
• Molecular Formula: C6H2ClN3O3
• Synonyms: 4-Chloro-7-nitrobenzofurazan
• IUPAC Name: 4-chloro-7-nitro-2,1,3-benzoxadiazole
• Canonical SMILES: C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]
• InChI: InChI=1S/C6H2ClN3O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H
• InChI Key: IGHBXJSNZCFXNK-UHFFFAOYSA-N
• Boiling Point: 333.1 ± 45.0 °C
• Melting Point: 97 - 99 °C
• Density: 2.0589 g/ml
• Appearance: Yellow to light brown crystalline powder
• Storage: Freeze(<-15 °C); Minimizelightexposure
• Emission Maximum: 539 nm
• Excitation Maximum: 467 nm

Synthetic Use

Downstream Synthesis Route 1

• 463-71-8
• 10199-89-0

• 17417-09-3
• 39835-09-1

Reference: [1] Journal of Fluorine Chemistry, 1997, vol. 85, # 2, p. 169 - 172
[2] Journal of Fluorine Chemistry, 1997, vol. 85, # 2, p. 169 - 172

Downstream Synthesis Route 2

• 463-71-8
• 10199-89-0

• 17417-09-3
• 39835-09-1
• 57381-56-3

Reference: [1] Journal of Fluorine Chemistry, 1997, vol. 85, # 2, p. 169 - 172

Downstream Synthesis Route 3

• 10199-89-0
• 100-46-9

• 18378-20-6

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 1, p. 370 - 374
[2] Journal fuer Praktische Chemie (Leipzig), 1985, vol. 327, # 3, p. 487 - 504
[3] Journal of Medicinal Chemistry, 1968, vol. 11, # 2, p. 305 - 311

Downstream Synthesis Route 4

• 100-53-8
• 10199-89-0

• 16322-24-0

Reference: [1]Kessler, Ulrich; Castagnolo, Daniele; Pagano, Mafalda; Deodato, Davide; Bernardini, Martina; Pilger, Beatrice; Ranadheera, Charlene; Botta, Maurizio
[Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 20, p. 5575 - 5577]
[2]Rotili, Dante; De Luca, Anastasia; Tarantino, Domenico; Pezzola, Silvia; Forgione, Mariantonietta; Della Rocca, Blasco Morozzo; Falconi, Mattia; Mai, Antonello; Caccuri, Anna Maria
[European Journal of Medicinal Chemistry, 2015, vol. 89, p. 156 - 171]
[3]Ghosh,P.B.; Whitehouse,M.W.
[Journal of Medicinal Chemistry, 1968, vol. 11, # 2, p. 305 - 311]
[4]Gautam, Nagsen; Thakare, Rhishikesh; Rana, Sandeep; Natarajan, Amarnath; Alnouti, Yazen
[Xenobiotica, 2015, vol. 45, # 10, p. 858 - 873]

Downstream Synthesis Route 5

• 10199-89-0
• 100-46-9

• 18378-20-6

Reference: [1]Yap, Jeremy L.; Wang, Huabo; Hu, Angela; Chauhan, Jay; Jung, Kwan-Young; Gharavi, Robert B.; Prochownik, Edward V.; Fletcher, Steven
[Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 1, p. 370 - 374]
[2]Heberer, H.; Kersting, H.; Matschiner, H.
[Journal fur praktische Chemie (Leipzig 1954), 1985, vol. 327, # 3, p. 487 - 504]
[3]Ghosh,P.B.; Whitehouse,M.W.
[Journal of Medicinal Chemistry, 1968, vol. 11, # 2, p. 305 - 311]

* For details of the synthesis route, please refer to the original source to ensure accuracy.