Structure

N-Ethylmaleimide

CAS
128-53-0
Catalog Number
ACM-MO-128530
Category
Inhibitors; Cyclic Olefin Monomers
Molecular Weight
125.13 g/mol
Molecular Formula
C6H7NO2

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Specification

Description
N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides.
Synonyms
NEM
IUPAC Name
1-ethylpyrrole-2,5-dione
Canonical SMILES
CCN1C(=O)C=CC1=O
InChI Key
HDFGOPSGAURCEO-UHFFFAOYSA-N
Boiling Point
210 °C
Melting Point
46 °C
Flash Point
73ºC
Density
1.207 g/cm³
Solubility
Soluble in water.
Appearance
White Powder to Crystal
Storage
0-10 °C
Condition To Avoid
Light Sensitive,Air Sensitive,Heat Sensitive
EC Number
204-892-4
Exact Mass
125.04800
Hazard Statements
T+:Verytoxic;
Packing Group
II
Physical State
Solid
Safety Description
S26-S28-S36/37/39-S45
Shipping
Can be shipped at room temperature, where not in use may vary.
Stability
Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate.
WGK Germany
3
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