N-Boc-nortropine

• CAS: 143557-91-9
• Catalog Number: ACM143557919
• Category: Other Products
• Molecular Weight: 227.300040 [g/mol]
• Molecular Formula: C₁₂H₂₁NO₃
• Synonyms: N-Boc-Nortropine;tert-Butyl 3-endo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
• IUPAC Name: tert-butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
• Canonical SMILES: CC(C)(C)OC(=O)N1C2CCC1CC(C2)O
• InChI Key: SEGZJJSZYOEABC-UHFFFAOYSA-N
• Boiling Point: 327.9ºC at 760 mmHg
• Flash Point: 152.1ºC
• Density: 1.146g/cm³
• Exact Mass: 227.15200
• H-Bond Acceptor: 3
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 24424-99-5
• 538-09-0

• 143557-91-9

Reference: [1] Patent: WO2007/63071, 2007, A1, . Location in patent: Page/Page column 15

Upstream Synthesis Route 2

• 936701-56-3

• 143557-91-9

Reference: [1] Patent: US2012/4257, 2012, A1, . Location in patent: Page/Page column 7

Upstream Synthesis Route 3

• 24424-99-5
• 538-09-0

• 143557-91-9

Reference: [1]Patent: WO2007/63071,2007,A1 .Location in patent: Page/Page column 15

Upstream Synthesis Route 4

• 34619-03-9
• 538-09-0

• 143557-91-9

Reference: [1]Patent: WO2007/93365,2007,A2 .Location in patent: Page/Page column 93; 100-101

Upstream Synthesis Route 5

• 652148-00-0
• 34619-03-9

• 194222-05-4
• 143557-91-9

Reference: [1]Patent: WO2004/9588,2004,A1 .Location in patent: Page 49

Downstream Synthesis Route 1

• 143557-91-9

• 14383-51-8

Reference: [1] Patent: US2007/66584, 2007, A1, . Location in patent: Page/Page column 30

* For details of the synthesis route, please refer to the original source to ensure accuracy.