Methyl 2-acetamidoacrylate

• CAS: 35356-70-8
• Catalog Number: ACM35356708-1
• Category: Polymer/Macromolecule
• Molecular Weight: 143.14
• Molecular Formula: H2C=C(NHCOCH3)CO2CH3
• Description: Conjugated addition of secondary amines, imidazole and pyrazole to methyl 2 methyl 2-acetamidoacrylate in the presence of a catalyst results in the formation of β-Dialkylamino-α-alanine and β-(N-heteroaryl)-α-alanine derivatives. Methyl-2-acetamidoacrylate (M2AA) is an anti-inflammatory agent. The catalytic reaction of methyl 2-acetamidoacrylate with Grignard's reagents affords α-amino esters. M2AA can form thermosensitive copolymers with methyl acrylate. Methyl ester of 2-acetamidoacrylate . methyl 2-acetamidoacrylate (Me-2-AA) is a di-unsaturated α-amino acid derivative. methyl-2-acetamidoacrylate exihibits anti -inflammatory properties, it is very effective against lipopolysaccharide (LPS)- induced nitric oxide production by RAW 264.
• Synonyms: 2-ACETAMIDOACRYLIC ACID METHYL ESTER;METHYL 2-ACETAMIDOACRYLATE;Ac-DL-Dha-OMe~2-Acetamidoacrylic acid methyl ester~N-Acetyldehydroalanine methyl ester;2-ACETAMIDOACRYLIC ACID METHYL ESTER 95+%;ac-dl-dha-ome;2-Acetylaminoacrylic acid methyl ester;Methyl 2-
• Canonical SMILES: COC(=O)C(=C)NC(C)=O
• InChI: 1S/C6H9NO3/c1-4(6(9)10-3)7-5(2)8/h1H2,2-3H3,(H,7,8)
• InChI Key: SMWNFFKPVLVOQQ-UHFFFAOYSA-N
• Boiling Point: 104 °C/8 mmHg (lit.)
• Melting Point: 50-52 °C (lit.)
• Application: Methyl 2-acetamidoacrylate can undergo [2+2] cycloaddition (Michael-Dieckmann-type reaction) with ketene diethyl acetal to yield the cyclobutane core. It may be used in rhodium-catalyzed 2-alkenylpyrrole formation.
• Assay: 98%
• Features And Benefits: 1. High quality products; 2. Fast delivery; 3. Additional products can be ordered, please contact us for details
• MDL Number: MFCD00013394
• Packaging: Packaging; 1, 5 g in glass bottle
• PubChem ID: 24859082
• Quality Level: 100

Custom Q&A

What is the molecular weight of Methyl 2-acetamidoacrylate?

The molecular weight of Methyl 2-acetamidoacrylate is 143.14.

What is the molecular formula of Methyl 2-acetamidoacrylate?

The molecular formula of Methyl 2-acetamidoacrylate is H2C=C(NHCOCH3)CO2CH3.

What is the boiling point of Methyl 2-acetamidoacrylate?

The boiling point of Methyl 2-acetamidoacrylate is 104 °C/8 mmHg (lit.).

How does Methyl 2-acetamidoacrylate exhibit anti-inflammatory properties?

Methyl 2-acetamidoacrylate exhibits anti-inflammatory properties by being effective against lipopolysaccharide (LPS)-induced nitric oxide production by RAW 264.

What are some synonyms for Methyl 2-acetamidoacrylate?

Some synonyms for Methyl 2-acetamidoacrylate include 2-ACETAMIDOACRYLIC ACID METHYL ESTER and Ac-DL-Dha-OMe~2-Acetamidoacrylic acid methyl ester.

What applications can Methyl 2-acetamidoacrylate be used for?

Methyl 2-acetamidoacrylate can undergo [2+2] cycloaddition (Michael-Dieckmann-type reaction) with ketene diethyl acetal to yield a cyclobutane core. It may be used in rhodium-catalyzed 2-alkenylpyrrole formation.

What catalytic reaction of Methyl 2-acetamidoacrylate with Grignard's reagents affords?

The catalytic reaction of Methyl 2-acetamidoacrylate with Grignard's reagents affords α-amino esters.

What derivatives can be formed through the conjugated addition of secondary amines, imidazole, and pyrazole to Methyl 2-acetamidoacrylate?

The conjugated addition of secondary amines, imidazole, and pyrazole to Methyl 2-acetamidoacrylate results in the formation of β-Dialkylamino-α-alanine and β-(N-heteroaryl)-α-alanine derivatives.

What is the quality level of Methyl 2-acetamidoacrylate?

The quality level of Methyl 2-acetamidoacrylate is 100.

How can Methyl 2-acetamidoacrylate be stored?

Methyl 2-acetamidoacrylate is packaged in 1, 5 g glass bottles for storage.