Structure

Megestrol acetate

CAS
595-33-5
Catalog Number
ACM595335
Category
Inhibitors
Molecular Weight
384.52
Molecular Formula
C24H32O4

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Specification

Description
Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway.
Synonyms
Megestrol acetate; [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate;
IUPAC Name
megestrol acetate
Canonical SMILES
CC([C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])C=C(C)C4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
Boiling Point
507.1ºC at 760mmHg
Melting Point
214ºC
Flash Point
218.5ºC
Density
1.15g/cm³
Appearance
Crystalline Solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Exact Mass
384.23000
Hazard Statements
Xn:Harmful
Safety Description
S22-S24/25
Shipping
Can be shipped at room temperature, where not in use may vary.
WGK Germany
3
What is the molecular formula of megestrol acetate?

The molecular formula of megestrol acetate is C24H32O4.

What is the molecular weight of megestrol acetate?

The molecular weight of megestrol acetate is 384.5 g/mol.

What is megestrol acetate used for?

Megestrol acetate is used as an appetite stimulant for the treatment of anorexia and cachexia. It is also used for birth control and the treatment of breast cancer.

How is megestrol acetate related to megestrol?

Megestrol acetate is functionally related to megestrol, as it is a steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid.

What is the IUPAC name of megestrol acetate?

The IUPAC name of megestrol acetate is [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate.

What is the InChIKey of megestrol acetate?

The InChIKey of megestrol acetate is RQZAXGRLVPAYTJ-GQFGMJRRSA-N.

What is the CAS number of megestrol acetate?

The CAS number of megestrol acetate is 595-33-5.

What is the EC number of megestrol acetate?

The EC number of megestrol acetate is 209-864-5.

What is the UNII of megestrol acetate?

The UNII of megestrol acetate is TJ2M0FR8ES.

What is the ChEMBL ID of megestrol acetate?

The ChEMBL ID of megestrol acetate is CHEMBL1201139.

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