Structure

Mefloquine hydrochloride

CAS
51773-92-3
Catalog Number
ACM51773923
Category
Inhibitors
Molecular Weight
414.77
Molecular Formula
C17H17ClF6N2O

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Specification

Description
Mefloquine hydrochloride (Mefloquin hydrochloride), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine hydrochloride is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine hydrochloride can be used for malaria, systemic lupus erythematosus and cancer research.
Synonyms
Mefloquine HCL
Appearance
White powder
What is the molecular formula of Mefloquine hydrochloride?

The molecular formula of Mefloquine hydrochloride is C17H17ClF6N2O.

What is the molecular weight of Mefloquine hydrochloride?

The molecular weight of Mefloquine hydrochloride is 414.8 g/mol.

What is the parent compound of Mefloquine hydrochloride?

The parent compound of Mefloquine hydrochloride is Mefloquine.

What are the synonyms for Mefloquine hydrochloride?

The synonyms for Mefloquine hydrochloride are Mefloquine HCL, 51773-92-3, Mephaquin, and Loriam.

What is the exact mechanism of Mefloquine hydrochloride?

The exact mechanism of Mefloquine hydrochloride is largely unknown, but it is believed to act as a blood schizonticide by interacting with the phospholipid bilayer and destabilizing the cell membrane, leading to cell lysis.

What species of Plasmodium is Mefloquine hydrochloride active against?

Mefloquine hydrochloride is active against Plasmodium falciparum and Plasmodium vivax.

What is the IUPAC name of Mefloquine hydrochloride?

The IUPAC name of Mefloquine hydrochloride is (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol;hydrochloride.

What is the InChIKey of Mefloquine hydrochloride?

The InChIKey of Mefloquine hydrochloride is WESWYMRNZNDGBX-YLCXCWDSSA-N.

What is the CAS number of Mefloquine hydrochloride?

The CAS number of Mefloquine hydrochloride is 51773-92-3.

How many hydrogen bond acceptor count does Mefloquine hydrochloride have?

Mefloquine hydrochloride has a hydrogen bond acceptor count of 9.

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