Specification
Description
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
Mal-PEG2-CH2CH2COOH
IUPAC Name
3-[2-[2-(2,5-Dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid
Canonical SMILES
C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O
InChI
InChI=1S/C11H15NO6/c13-9-1-2-10(14)12(9)4-6-18-8-7-17-5-3-11(15)16/h1-2H,3-8H2,(H,15,16)
InChI Key
TXMDOUPVKVGPIS-UHFFFAOYSA-N
Boiling Point
455.7±35.0 °C at 760 mmHg
Flash Point
229.4±25.9 °C
Covalently-Bonded Unit Count
1
Monoisotopic Mass
257.0899372
Refractive Index
n20/D 1.526(lit.)
Topological Polar Surface Area
93.1 Ų
Type
Heterobifunctional PEG Linkers