Latrunculin A

• CAS: 76343-93-6
• Catalog Number: ACM76343936
• Category: Inhibitors
• Molecular Weight: 421.55
• Molecular Formula: C22H31NO5S
• Description: Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with Kds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration.
• Canonical SMILES: O=C1SC[C@@H]([C@]2(O)O[C@]3([H])CC[C@H](C)/C=C\C=C\CC/C(C)=C\C(O[C@@](C3)([H])C2)=O)N1
• Appearance: Liquid
• Storage: Solution, -20°C, 2 years
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: Red sea sponge Latrunculia magnifica