L-Methionine

• CAS: 63-68-3
• Catalog Number: ACM63683-2
• Category: Amino Acids
• Molecular Weight: 149.21
• Molecular Formula: CH3SCH2CH2CH(NH2)CO2H
• Synonyms: (S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid
• IUPAC Name: (2S)-2-Amino-4-methylsulfanylbutanoic acid
• Canonical SMILES: CSCC[C@H](N)C(O)=O
• InChI: 1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
• InChI Key: FFEARJCKVFRZRR-BYPYZUCNSA-N
• Boiling Point: 393.91 °C
• Melting Point: 284 ℃(dec.) (lit.)
• Flash Point: 139.4 °C
• Density: 1.34 g/cm
• Solubility: H2O: 25 mg/mL
• Appearance: White solid
• Application: L-Methionine has been used as a component of media to culture various cancer cells and to study its effects on the cell cycle. It has also been used as a component of DMEM medium to culture satellite cells from the white muscle of trouts.
• Storage: 20-25 °C
• Assay: 99.0-101.0%
• Beilstein: 1722294
• Biochem Physiol Actions: Methionine is an essential amino acid which acts a precursor for transmethylation and transsulphuration. In proteins, L-methionine is the biologically active form. The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), which serves as a methyl donor to various substances. L-Methionine's metabolic product glutathione is known to regulate immune response and has antiviral action.
• Biological Source: non-animal source
• Color: white
• Color/Form: Minute hexagonal plates from dilute alcohol;Colorless or white, lustrous plates or as white, crystalline powder
• Complexity: 97
• Covalently-Bonded Unit Count: 1
• Decomposition: When heated to decomposition it emits very toxic fumes of /nitric oxide/ and /sulfur oxide/.
• Defined Atom Stereocenter Count: 1
• EC Number: 200-562-9
• Exact Mass: 149.05104977
• Form: powder
• Gene Information: rat Ggt1(116568)
• H-Bond Acceptor: 4
• H-Bond Donor: 2
• Heavy Atom Count: 9
• Impurity Content: endotoxin, tested
• Isomeric SMILES: CSCC[C@@H](C(=O)O)N
• MDL Number: MFCD00063097
• Monoisotopic Mass: 149.05104977
• NACRES: NA.26
• NSC Number: 760117
• Octanol Water Partition Coefficient: -1.87 (LogP);log Kow = -1.87;-1.87
• Odor: Faint
• Other Experimental: Specific optical rotation: +8.12 deg at 25 deg C/D (c = 0.8); -21.19 deg at 25 deg C/D (c = 0.8 in 0.2N HCl) /Methione, D-form/;Platelets from alcohol. mp 281 deg C (decomposes), density 1.340; pKa1 = 2.28, pKa2 = 9.21; pH of 1% aqueous solution 5.6-6.1; Rf value 0.77. Solubility in water (g/L) at 0 deg C: 18.18; at 25 deg C: 33.81; at 50 deg C: 60/.70; at 75 deg C: 15.2 deg C. Soluble in dilute acids, alkalies. Very slightly soluble in 95% alcohol. Insoluble in ether. /Methionine, DL-form/;IR: 2549 (Coblentz Society Spectral Collection) /Methionine (DL)/;UV: 1-65 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Methionine (DL)/;13C NMR: 135 (Johnson and Jankowski, Carbon-13 NMR Spectra, John Wiley & Sons, New York) /Methionine (DL)/;MASS: 442 (National Bureau of Standards EPA-NIH Mass Spectra Data Base, NSRDS-NBS-63) /Methionine (DL)/;Henry's Law constant = 2.11X10-11 atm-cu m/mol at 25 deg C (est);Hydroxyl radical reaction rate constant = 5.13X10-11 cu cm/molec-sec at 25 deg C (est)
• pH: 5.6-6.1 (1%, H₂O)
• Physical Description: Minute hexagonal plates from dilute alcohol. (NTP, 1992);Solid
• Physical State: Liquid
• pKa: 2.13(at 25 °C)
• PubChem ID: 24896818
• Quality Level: 300
• Refractive Index: 1.5216
• Rotatable Bond Count: 4
• Storage Temperature: 2-8℃
• Technique: cell culture | mammalian: suitable
• Topological Polar Surface Area: 88.6 Ų
• Undefined Atom Stereocenter Count: 1
• UNII: AE28F7PNPL
• Vapor Pressure: 8.14X10-8 mm Hg at 25 deg C (est)

Custom Q&A

What is the PubChem CID for L-Methionine?

The PubChem CID for L-Methionine is 6137.

What is the molecular formula of L-Methionine?

The molecular formula of L-Methionine is C5H11NO2S.

What is the molecular weight of L-Methionine?

The molecular weight of L-Methionine is 149.21 g/mol.

What is the IUPAC name of L-Methionine?

The IUPAC name of L-Methionine is (2S)-2-amino-4-methylsulfanylbutanoic acid.

What is the InChI of L-Methionine?

The InChI of L-Methionine is InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1.

What is the InChIKey of L-Methionine?

The InChIKey of L-Methionine is FFEARJCKVFRZRR-BYPYZUCNSA-N.

What are the synonyms of L-Methionine?

The synonyms of L-Methionine are L-methionine, 63-68-3, methionine, h-Met-oh, (S)-2-Amino-4-(methylthio)butanoic acid.

What is the role of L-Methionine in the body?

L-Methionine has a role as a nutraceutical, a micronutrient, an antidote to paracetamol poisoning, a human metabolite, and a mouse metabolite.

Is L-Methionine a chelating agent for heavy metals?

Yes, L-Methionine is a chelating agent for heavy metals.

What is the CAS number of L-Methionine?

The CAS number of L-Methionine is 63-68-3.