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L-2-Hydroxyglutaric Acid

CAS
13095-48-2
Catalog Number
ACM13095482
Category
Inhibitors
Molecular Weight
148.11
Molecular Formula
C5H8O5
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Description
L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively.
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