L-Aspartic acid β-benzyl ester

• CAS: 2177-63-1
• Catalog Number: ACM2177631
• Category: Amino Acids
• Molecular Weight: 223.23
• Molecular Formula: C6H5CH2OCOCH2CH(NH2)COOH
• Synonyms: β-Benzyl L-aspartate, L-Aspartic acid 4-benzyl ester
• Canonical SMILES: N[C@@H](CC(=O)OCc1ccccc1)C(O)=O
• InChI: 1S/C11H13NO4/c12-9(11(14)15)6-10(13)16-7-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,14,15)/t9-/m0/s1
• InChI Key: VGALFAWDSNRXJK-VIFPVBQESA-N
• Melting Point: 225℃
• Application: L-Aspartic acid β-benzyl ester is used in the synthesis of peptides with a 1,4-diazepine-2,5-dione ring structure and in development of block copolymers.
• Assay: ≥98%
• Beilstein: 1983183
• Color: white
• EC Number: 218-541-8
• Form: powder
• MDL Number: MFCD00037208
• NACRES: NA.26
• PubChem ID: 24891628
• Quality Level: 200
• Storage Temperature: -20℃

Synthetic Use

Downstream Synthesis Route 1

• 32315-10-9
• 2177-63-1

• 13590-42-6

Reference: [1] Journal of Drug Delivery Science and Technology, 2018, vol. 45, p. 281 - 286

Downstream Synthesis Route 2

• 75-44-5
• 2177-63-1

• 13590-42-6

Reference: [1] Chemistry - A European Journal, 2018, vol. 24, # 54, p. 14373 - 14377
[2] Archiv der Pharmazie, 2006, vol. 339, # 6, p. 283 - 290
[3] Archiv der Pharmazie, 2001, vol. 334, # 6, p. 189 - 193
[4] Bulletin de la Societe Chimique de France, 1971, p. 4387 - 4391

Downstream Synthesis Route 3

• 2177-63-1
• 503-38-8

• 13590-42-6

Reference: [1] Synthetic Communications, 2017, vol. 47, # 1, p. 53 - 61
[2] Journal of Organic Chemistry, 1985, vol. 50, # 5, p. 715 - 716
[3] Acta Crystallographica Section C: Crystal Structure Communications, 2003, vol. 59, # 3, p. o159-o161

Downstream Synthesis Route 4

• 18595-34-1
• 2177-63-1

• 7536-58-5

Reference: [1]Justus Liebigs Annalen der Chemie,1968,vol. 716,p. 175 - 185

Downstream Synthesis Route 5

• 2177-63-1
• 25474-85-5

• 4427-49-0

Reference: [1]Chemical and pharmaceutical bulletin,1971,vol. 19,p. 420 - 423

* For details of the synthesis route, please refer to the original source to ensure accuracy.