Indoxacarb

• CAS: 173584-44-6
• Catalog Number: ACM173584446
• Category: Main Products
• Molecular Weight: 527.83
• Molecular Formula: C₂₂H₁₇ClF₃N₃O₇
• Synonyms: methyl (S)-N-[7-chloro-2,3,4a,5-tetrahydro-4a-(methoxycarbonyl)indeno[1,2-e][1,3,4]oxadiazin-2-ylcarbonyl]-4'-(trifluoromethoxy)carbanilate; INDOXACARB; methyl (S)-7-chloro-2,3,4a,5-tetrahydro-2-[methoxycarbonyl(4-trifluoromethoxyphenyl)carbamoyl]indeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate; methyl (4aS)-7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate; carb
• IUPAC Name: methyl(4aS)-7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
• Canonical SMILES: COC(=O)C12CC3=C(C1=NN(CO2)C(=O)N(C4=CC=C(C=C4)OC(F)(F)F)C(=O)OC)C=CC(=C3)Cl
• InChI Key: VBCVPMMZEGZULK-NRFANRHFSA-N
• Boiling Point: 571.4ºC at 760 mmHg
• Melting Point: 88.1ºC
• Flash Point: 299.3ºC
• Density: 1.53g/cm³
• EC Number: 605-683-4
• Exact Mass: 527.07100

Case Study

Indoxacarb-Based Deep Eutectic Solvent System for Enhanced Lethal Activity Against Red Imported Fire Ants

Fu J, et al. Ecotoxicology and Environmental Safety, 2025, 289, 117709.

Indoxacarb (IDC) was formulated into deep eutectic solvents (DESs) with three fatty acids-oleic acid (OA), linoleic acid (LA), and linolenic acid (LNA)-to develop a DES-CaCO3 system with enhanced insecticidal effects against red imported fire ants (RIFAs). The DESs, prepared by combining IDC and fatty acids in a 1:1 molar ratio under vacuum and controlled heating conditions, demonstrated significantly improved lethal activity compared to IDC alone. Further screening of eutectic solvent ratios (1:2, 1:3, and 1:5) confirmed optimal stability and dispersibility for a 1:1 mixture.
To address water insolubility, green emulsifiers were incorporated to improve dispersion, enabling efficient coating applications. The DES-CaCO3 nanoparticles were synthesized via interfacial precipitation, involving the reaction of the emulsified DESs in calcium chloride and sodium carbonate solutions. The resulting OA@IDC@CaCO3, LA@IDC@CaCO3, and LNA@IDC@CaCO3 systems exhibited improved bioavailability and stability, effectively regulating RIFA behavior and achieving superior contact and feeding-based insecticidal activity.

Custom Q&A

What is the molecular formula of indoxacarb?

The molecular formula of indoxacarb is C22H17ClF3N3O7.

What are some synonyms for indoxacarb?

Some synonyms for indoxacarb include Steward, Provaunt, Advion, Avaunt, and Avatar.

What is the chemical name for indoxacarb?

The chemical name for indoxacarb is methyl (4aS)-7-chloro-2-[methoxycarbonyl-(4-(trifluoromethoxy)phenyl)carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate.

Is indoxacarb an insecticide?

Yes, indoxacarb is an insecticide.

What is the structure of indoxacarb?

The structure of indoxacarb is shown in the provided images (Indoxacarb2d.png and Indoxacarb3d.png).

What is the CAS number of indoxacarb?

The CAS number of indoxacarb is 173584-44-6.

What is the role of indoxacarb?

Indoxacarb acts as a voltage-gated sodium channel blocker.

What are the health hazards associated with indoxacarb?

The reference mentions indoxacarb as an acute toxic, health hazard, and environmental hazard. However, specific details about health hazards are not provided.

What is the IUPAC name of indoxacarb?

The IUPAC name of indoxacarb is methyl (4aS)-7-chloro-2-[methoxycarbonyl-(4-(trifluoromethoxy)phenyl)carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate.

What is the UNII number of indoxacarb?

The UNII number of indoxacarb is 52H0D26MWR.