Specification
Description
Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
Hydroxy-PEG4-propionic acid
IUPAC Name
3-[2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES
C(COCCOCCOCCOCCO)C(=O)O
InChI
InChI=1S/C11H22O7/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h12H,1-10H2,(H,13,14)
InChI Key
UQWLGZFJGVEDCQ-UHFFFAOYSA-N
Boiling Point
420.7±40.0 °C at 760 mmHg
Flash Point
155.5±20.8 °C
Covalently-Bonded Unit Count
1
Monoisotopic Mass
266.13655304
Refractive Index
n20/D 1.466(lit.)
Topological Polar Surface Area
94.4 Ų
Type
Heterobifunctional PEG Linkers