Hexaethylene glycol di-p-toluenesulfonate

• CAS: 42749-27-9
• Catalog Number: ACM42749279-1
• Category: Other Products
• Molecular Weight: 590.70
• Molecular Formula: C26H38O11S2
• Description: Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.
• Synonyms: HEG ditosylate, Hexaethylene glycol ditosylate
• IUPAC Name: 2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
• Canonical SMILES: Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOS(=O)(=O)c2ccc(C)cc2
• InChI: 1S/C26H38O11S2/c1-23-3-7-25(8-4-23)38(27,28)36-21-19-34-17-15-32-13-11-31-12-14-33-16-18-35-20-22-37-39(29,30)26-9-5-24(2)6-10-26/h3-10H,11-22H2,1-2H3
• InChI Key: ZIZXHPCBPDNLDD-UHFFFAOYSA-N
• Boiling Point: 687.4ºC at 760 mmHg
• Flash Point: 369.5ºC
• Density: 1.227 g/mL at 25 °C
• Application: Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.
• Assay: >97%
• Exact Mass: 590.18600
• Features And Benefits: 1. High quality products; 2. Fast delivery; 3. Additional products can be ordered, please contact us for details
• H-Bond Acceptor: 11
• H-Bond Donor: 0
• MDL Number: MFCD00319275
• NACRES: NA.23
• PubChem ID: 329764834
• Quality Level: 100
• Refractive Index: n20/D 1.521

Custom Q&A

What is the molecular formula of Hexaethylene glycol di-p-toluenesulfonate?

The molecular formula of Hexaethylene glycol di-p-toluenesulfonate is C26H38O11S2.

What is the IUPAC Name of Hexaethylene glycol di-p-toluenesulfonate?

The IUPAC Name of Hexaethylene glycol di-p-toluenesulfonate is 2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate.

What is the assay percentage of Hexaethylene glycol di-p-toluenesulfonate?

The assay percentage of Hexaethylene glycol di-p-toluenesulfonate is >97%.

What are some synonyms for Hexaethylene glycol di-p-toluenesulfonate?

Some synonyms for Hexaethylene glycol di-p-toluenesulfonate are HEG ditosylate and Hexaethylene glycol ditosylate.

What category does Hexaethylene glycol di-p-toluenesulfonate belong to?

Hexaethylene glycol di-p-toluenesulfonate belongs to the category of Other Homobifunctional PEG.

What is the molecular weight of Hexaethylene glycol di-p-toluenesulfonate?

The molecular weight of Hexaethylene glycol di-p-toluenesulfonate is 590.70.

What is the SMILES notation for Hexaethylene glycol di-p-toluenesulfonate?

The SMILES notation for Hexaethylene glycol di-p-toluenesulfonate is Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOS(=O)(=O)c2ccc(C)cc2.

What are some applications of activated PEG derivatives like Hexaethylene glycol di-p-toluenesulfonate?

Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology.

What are some features and benefits of Hexaethylene glycol di-p-toluenesulfonate?

Some features and benefits of Hexaethylene glycol di-p-toluenesulfonate include high quality products, fast delivery, and the option to order additional products.

What is the PubChemID of Hexaethylene glycol di-p-toluenesulfonate?

The PubChemID of Hexaethylene glycol di-p-toluenesulfonate is 329764834.

Synthetic Use

Upstream Synthesis Route 1

• 2615-15-8
• 98-59-9

• 42749-27-9

Reference: [1]Bioorganic and Medicinal Chemistry,2010,vol. 18,p. 5732 - 5737

Downstream Synthesis Route 1

• 42749-27-9

• 189209-27-6

Reference: [1] Patent: EP3321279, 2018, A1,

Downstream Synthesis Route 2

• 1852-17-1
• 42749-27-9

• 69928-21-8

Reference: [1]Journal of Organic Chemistry,1979,vol. 44,p. 2226 - 2233

Downstream Synthesis Route 3

• 1852-17-1
• 42749-27-9

• 69928-22-9

Reference: [1]Journal of Organic Chemistry,1979,vol. 44,p. 2226 - 2233

* For details of the synthesis route, please refer to the original source to ensure accuracy.