Guanidinosuccinic acid

• CAS: 6133-30-8
• Catalog Number: ACM6133308
• Category: Main Products
• Molecular Weight: 175.14 g/mol
• Molecular Formula: C5H9N3O4
• Synonyms: Guanidinosuccinic acid; NSC 49078; NSC-49078; NSC49078; L-N-Amidinoaspartic acid
• IUPAC Name: carbamimidoyl-L-aspartic acid
• Canonical SMILES: O=C(O)C[C@@H](C(O)=O)NC(N)=N
• InChI: InChI=1S/C5H9N3O4/c6-5(7)8-2(4(11)12)1-3(9)10/h2H,1H2,(H,9,10)(H,11,12)(H4,6,7,8)/t2-/m0/s1
• InChI Key: VVHOUVWJCQOYGG-REOHCLBHSA-N
• Boiling Point: 366.9ºC at 760 mmHg
• Flash Point: 175.7ºC
• Density: 1.74g/cm³
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• Drug Formulation: This drug may be formulated in DMSO
• Elemental Analysis: C, 34.29; H, 5.18; N, 23.99; O, 36.54
• Exact Mass: 175.0593
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Custom Q&A

What is the molecular formula of Guanidinosuccinic acid?

The molecular formula of Guanidinosuccinic acid is C5H9N3O4.

What are the synonyms for Guanidinosuccinic acid?

The synonyms for Guanidinosuccinic acid are N-Amidino-L-aspartic acid and Guanidinosuccinate.

What is the molecular weight of Guanidinosuccinic acid?

The molecular weight of Guanidinosuccinic acid is 175.14 g/mol.

What is the IUPAC name of Guanidinosuccinic acid?

The IUPAC name of Guanidinosuccinic acid is (2S)-2-(diaminomethylideneamino)butanedioic acid.

In which organisms is Guanidinosuccinic acid found?

Guanidinosuccinic acid is found in Diospyros virginiana, Malus pumila, and other organisms.

What type of compound is Guanidinosuccinic acid in terms of uremic toxins?

Guanidinosuccinic acid is a uremic toxin.

How does Guanidinosuccinic acid arise metabolically?

Guanidinosuccinic acid arises from the oxidation of argininosuccinic acid (ASA) by free radicals.

What is the effect of uremic toxins like Guanidinosuccinic acid on the body?

Chronic exposure to uremic toxins like Guanidinosuccinic acid can lead to conditions such as renal damage, chronic kidney disease, and cardiovascular disease.

How can the build-up of Guanidinosuccinic acid be reduced in end-stage renal disease?

The build-up of Guanidinosuccinic acid in end-stage renal disease can be reduced by replacing specific amino acid mixtures and monitoring serum levels of related toxins.

What is another name for Guanidinosuccinic acid in the Toxin and Toxin Target Database?

In the Toxin and Toxin Target Database, Guanidinosuccinic acid is also referred to as (2S)-2-(diaminomethylideneamino)butanedioic acid.

Synthetic Use

Upstream Synthesis Route 1

• 56-84-8
• 2986-19-8

• 6133-30-8

Reference: [1]Ratner et al.
[Journal of Biological Chemistry, 1953, vol. 204, p. 95,108]

Upstream Synthesis Route 2

• 56-84-8
• 2440-60-0

• 6133-30-8

Reference: [1]Walker
[Archives of Biochemistry, 1955, vol. 59, p. 233,234, 240]

Upstream Synthesis Route 3

• 56-84-8
• 867-44-7

• 6133-30-8

Reference: [1]Pant,E.
[Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1964, vol. 335, p. 272 - 274]