58130-03-3 Purity
Tech
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Specification
A vitamin
Folic acid has a positive effect on cell division and growth and the synthesis of nutrients.
Folic acid is stable to visible light, the activity is reduced by ultraviolet light, and the oxidative hydrolysis is accelerated by acid and alkali.
pKa 2.5
The structure of folic acid consists of a nystatin, which is conjugated to nystatin (nystatinyl) adjacent to p-aminobenzoic acid through a methylene bridge, and then combined with glutamic acid.
200-419-0
Yellow to orange crystalline powder
OVBPIULPVIDEAO-LBPRGKRZSA-N
1.68
20 º (c=1, 0.1N NaOH)
Folic acid can be synthesized by first synthesizing the pteridine nucleus and then condensing it with p-aminobenzoylglutamic acid to obtain folic acid, or crude folic acid can be obtained from the reaction of 2,4,5-triamino-6-hydroxypyrimidines, α,β-dibromopropanal, and p-aminobenzoylglutamic acid in acetic acid-sodium acetate buffer solution, which can be refined to obtain folic acid containing two molecules of water of crystallization. Similar to the latter Hop Chemicalbook method, p-aminobenzoylglutamic acid, trichloroacetone and 2,4,5-triamino-6-hydroxypyrimidine sulfate ([1603-20-7]) were cyclized for 6 h in the presence of sodium acetate and sodium metabisulfite, maintaining pH 3.4-3.6, and at a temperature of 36-40°C to give an orange-red folic acid precipitate
Folic acid is absorbed in the body in two ways, actively and diffusely passively, and the site of absorption is mainly in the upper part of the small intestine.